Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase (Q24290421)

response to iron ion starvation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

J Shao

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N Grammatikakis

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B T Scroggins

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S Uma

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W Huang

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J J Chen

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S D Hartson

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R L Matts

Journal of Biological Chemistry

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language of work or name

English

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publication date

5 January 2001

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published in

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volume

276

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issue

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page(s)

206-14

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cites work

Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Hsp90 is obligatory for the heme-regulated eIF-2alpha kinase to acquire and maintain an activable conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Dual role for Hsc70 in the biogenesis and regulation of the heme-regulated kinase of the alpha subunit of eukaryotic translation initiation factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Hold 'em and fold 'em: chaperones and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Protein folding and the regulation of signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Chaperone functions of the heat shock proteins associated with steroid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

A Novel Glycosaminoglycan-binding Protein Is the Vertebrate Homologue of the Cell Cycle Control Protein, Cdc37

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Nucleotide sequence of the yeast cell division cycle start genes CDC28, CDC36, CDC37, and CDC39, and a structural analysis of the predicted products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Physical interaction of mammalian CDC37 with CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Cdc37 is a molecular chaperone with specific functions in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

CDC37 is required for p60v-src activity in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Cdc37 promotes the stability of protein kinases Cdc28 and Cak1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

p50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Temperature-sensitive ZAP70 mutants degrading through a proteasome-independent pathway. Restoration of a kinase domain mutant by Cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

The role of the 90-kDa heat-shock protein and its associated cohorts in stabilizing the heme-regulated eIF-2alpha kinase in reticulocyte lysates during heat stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Modular folding and evidence for phosphorylation-induced stabilization of an hsp90-dependent kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Evidence that Hsc70 negatively modulates the activation of the heme-regulated eIF-2alpha kinase in rabbit reticulocyte lysate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Denatured proteins inhibit translation in hemin-supplemented rabbit reticulocyte lysate by inducing the activation of the heme-regulated eIF-2 alpha kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Nucleotides and two functional states of hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

Molybdate inhibits hsp90, induces structural changes in its C-terminal domain, and alters its interactions with substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007583200

21 January 2018

Identifiers

DOI

10.1074/JBC.M007583200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

11036079

1 reference

Consolidated OpenCitations Corpus – April 2017