CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex (Q24290161)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0097058

Cardiotrophin like cytokine factor 1

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Ciliary neurotrophic factor

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Cytokine receptor like factor 1

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ciliary neurotrophic factor receptor binding

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author name string

G C Elson

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E Lelièvre

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C Guillet

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S Chevalier

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H Plun-Favreau

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J Froger

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I Suard

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A B de Coignac

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Y Delneste

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J Y Bonnefoy

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J F Gauchat

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H Gascan

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

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language of work or name

English

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publication date

September 2000

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867-72

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cites work

1 reference

Ciliary neurotrophic factor

21 January 2018

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Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy

21 January 2018

1 reference

Computational EST database analysis identifies a novel member of the neuropoietic cytokine family

21 January 2018

1 reference

Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family

21 January 2018

1 reference

Gp130 and the interleukin-6 family of cytokines

21 January 2018

1 reference

The receptor for ciliary neurotrophic factor

21 January 2018

1 reference

LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

21 January 2018

1 reference

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

21 January 2018

1 reference

Disruption of the CNTF gene results in motor neuron degeneration.

21 January 2018

1 reference

A null mutation in the human CNTF gene is not causally related to neurological diseases

21 January 2018

1 reference

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

21 January 2018

1 reference

The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development

21 January 2018

1 reference

Suckling defect in mice lacking the soluble haemopoietin receptor NR6.

21 January 2018

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Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

21 January 2018

1 reference

Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.

21 January 2018

1 reference

Signaling of the cardiotrophin-1 receptor. Evidence for a third receptor component.

21 January 2018

1 reference

Binding interactions of leukemia inhibitory factor and ciliary neurotrophic factor with the different subunits of their high affinity receptors

21 January 2018

1 reference

Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro

21 January 2018

1 reference

Ciliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease

21 January 2018

1 reference

A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group

21 January 2018

1 reference

Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients

21 January 2018

1 reference

Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease.

21 January 2018

1 reference

Essential function of LIF receptor in motor neurons

21 January 2018

1 reference

Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines

21 January 2018

1 reference

7 January 2021

Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor

1 reference

7 January 2021

Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury

1 reference

7 January 2021

Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF

1 reference

7 January 2021

Trophic effect of ciliary neurotrophic factor on denervated skeletal muscle

1 reference

7 January 2021

Ciliary neurotrophic factor is a regulator of muscular strength in aging

1 reference

7 January 2021

Cardiotrophin-1 requires LIFRbeta to promote survival of mouse motoneurons purified by a novel technique

1 reference

7 January 2021