RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling (Q24299327)

Axin 1

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Axin 2

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CASC3 exon junction complex subunit

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Ring finger protein 146

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Basic leucine zipper nuclear factor 1

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Tankyrase

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ubiquitin protein ligase binding

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signal transduction

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21478859

29 November 2024

author name string

Yue Zhang

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Shanming Liu

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Craig Mickanin

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Yan Feng

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Olga Charlat

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Markus Schirle

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Xiaoying Shi

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Marc Hild

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Andreas Bauer

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Feng Cong

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Gregory A. Michaud

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21478859

29 November 2024

Vic E. Myer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21478859

29 November 2024

Peter M. Finan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21478859

29 November 2024

Jeffery A. Porter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21478859

29 November 2024

Shih-Min A. Huang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21478859

29 November 2024

language of work or name

English

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publication date

May 2011

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10 April 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21478859

full work available at URL

29 November 2024

http://www.nature.com/articles/ncb2222.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/NCB2222

http://www.nature.com/articles/ncb2222

29 November 2024

1 reference

https://api.crossref.org/works/10.1038/NCB2222

29 November 2024

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623-9

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cites work

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21 January 2018

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The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway

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Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling

21 January 2018

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Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

21 January 2018

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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

21 January 2018

1 reference

Tankyrase function at telomeres, spindle poles, and beyond.

21 January 2018

1 reference

The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives.

21 January 2018

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Tankyrase recruitment to the lateral membrane in polarized epithelial cells: regulation by cell-cell contact and protein poly(ADP-ribosyl)ation

21 January 2018

1 reference

The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation

21 January 2018

1 reference

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

21 January 2018

1 reference

Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner

21 January 2018

1 reference

A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic

21 January 2018

1 reference

Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles

21 January 2018

1 reference

An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay

21 January 2018

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The age of crosstalk: phosphorylation, ubiquitination, and beyond

21 January 2018

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Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

21 January 2018

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DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics

21 January 2018

1 reference

E3 ubiquitin ligase that recognizes sugar chains

21 January 2018

1 reference

Poly(ADP-ribose): novel functions for an old molecule

21 January 2018

1 reference

The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases.

21 January 2018

1 reference

The macro domain is an ADP-ribose binding module

21 January 2018

1 reference

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

21 January 2018

1 reference

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

21 January 2018

1 reference

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

21 January 2018

1 reference

Wnt pathway and breast cancer

21 January 2018

1 reference

Wnt signaling and breast cancer

21 January 2018

1 reference

Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.

21 January 2018

1 reference

The poly(ADP-ribosylation) story: a long route from Cinderella to Princess

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21478859

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21478859