CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis (Q24297763)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094252%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis (English)

1 reference

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16 January 2020

0 references

1 reference

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16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094252%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Jiaying Tan

1 reference

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16 January 2020

Morgan Jones

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094252%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Manabu Nakayama

1 reference

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16 January 2020

Andrew G Muntean

1 reference

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16 January 2020

Jay L Hess

1 reference

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16 January 2020

language of work or name

English

0 references

publication date

1 November 2011

1 reference

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16 January 2020

1 reference

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16 January 2020

volume

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16 January 2020

issue

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16 January 2020

page(s)

563-575

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The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis

16 January 2020

cites work

1 reference

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19 March 2017

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A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription

19 March 2017

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Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus

19 March 2017

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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus

19 March 2017

1 reference

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A human protein-protein interaction network: a resource for annotating the proteome

19 March 2017

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Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

19 March 2017

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Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

19 March 2017

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MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

19 March 2017

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Cellular functions of TIP60

19 March 2017

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Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation

19 March 2017

1 reference

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Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice

19 March 2017

1 reference

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The polycomb protein MPc3 interacts with AF9, an MLL fusion partner in t(9;11)(p22;q23) acute leukemias

19 March 2017

1 reference

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The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3

19 March 2017

1 reference

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HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties

19 March 2017

1 reference

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MLL translocations, histone modifications and leukaemia stem-cell development

19 March 2017

1 reference

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ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

PAFc, a key player in MLL-rearranged leukemogenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Polycomb group complexes--many combinations, many functions

27 September 2017

1 reference

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MYST family histone acetyltransferases take center stage in stem cells and development.

27 September 2017

1 reference

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Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells

27 September 2017

1 reference

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H3K79 methylation profiles define murine and human MLL-AF4 leukemias

27 September 2017

1 reference

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HOX proteins and leukemia.

27 September 2017

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Menin critically links MLL proteins with LEDGF on cancer-associated target genes

27 September 2017

1 reference

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Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells

27 September 2017

1 reference

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Mechanisms of transcriptional regulation by MLL and its disruption in acute leukemia

27 September 2017

1 reference

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Protein arginine-methyltransferase-dependent oncogenesis

27 September 2017

1 reference

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A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification

27 September 2017

1 reference

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Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells

27 September 2017

1 reference

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Chromosomal translocations involving the MLL gene: molecular mechanisms

27 September 2017

1 reference

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Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.

27 September 2017

1 reference

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Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Functional interaction between the coactivator Drosophila CREB-binding protein and ASH1, a member of the trithorax group of chromatin modifiers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Male-to-female sex reversal in M33 mutant mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

The Oncogenic Capacity of HRX-ENL Requires the Transcriptional Transactivation Activity of ENL and the DNA Binding Motifs of HRX

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Polycomb Group proteins: an evolutionary perspective.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Trithorax and dCBP acting in a complex to maintain expression of a homeotic gene

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220883

Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22094252

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Licensed to elongate: a molecular mechanism for MLL-based leukaemogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22094252

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22094252

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CCR.2011.09.008

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094252%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094252%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

22094252

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094252%20AND%20SRC:MED&resulttype=core&format=json