Calcitonin/calcitonin-related polypeptide, alpha (Q14860528)

http://www.ebi.ac.uk/interpro/protein/P70160

Calcitonin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Calcitonin peptide-like family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

identical protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

signaling receptor binding

The calcitonin gene-related peptide (CGRP) phenotype is expressed early and up-regulated by resiniferatoxin (RTX) in mouse sensory neurons

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

TAS

14 February 2019

Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Characterization of a calcitonin gene-related peptide (CGRP) receptor on mouse bone marrow cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

calcitonin receptor binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Inhibitory effect of calcitonin gene-related peptide on myometrial contractility is diminished at parturition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

intracellular anatomical structure

cell component

2 references

10 September 2018

The calcitonin gene-related peptide (CGRP) phenotype is expressed early and up-regulated by resiniferatoxin (RTX) in mouse sensory neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

10 September 2018

Prenatal development of peptidergic primary afferent projections to mouse lumbosacral autonomic preganglionic cell columns

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

extracellular region

The calcitonin gene-related peptide (CGRP) phenotype is expressed early and up-regulated by resiniferatoxin (RTX) in mouse sensory neurons

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

14 February 2019

Peripherally administered calcitonin gene-related peptide decreases food intake in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

terminal bouton

4 references

14 February 2019

The innervation of calcitonin gene-related peptide to the Purkinje cells and granule cells in the developing mouse cerebellum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Mice lacking alpha-calcitonin gene-related peptide exhibit normal cardiovascular regulation and neuromuscular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

The origin and development of the vagal and spinal innervation of the external muscle of the mouse esophagus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Modulation of morphine analgesia in alphaCGRP mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

neuron projection

1 reference

14 February 2019

P2X3 knock-out mice reveal a major sensory role for urothelially released ATP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

extracellular space

Adaptive cytoprotection mediated by prostaglandin I(2) is attributable to sensitization of CRGP-containing sensory nerves

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

24 April 2018

Progesterone induction of calcitonin expression in the murine mammary gland

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

axon

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Calcitonin gene-related peptide (CGRP) in the developing mouse limb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Developmentally regulated expression of CGRP in the mouse olfactory pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Nerve fibers immunoreactive for substance P and calcitonin gene-related peptide in the cervical spinal ventral roots of the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Cholinergic chemosensory cells in the trachea regulate breathing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

neuronal cell body

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

24 April 2018

Reduced nociceptive behavior in islet amyloid polypeptide (amylin) knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

extracellular space

Adaptive cytoprotection mediated by prostaglandin I(2) is attributable to sensitization of CRGP-containing sensory nerves

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

monocyte chemotaxis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

positive regulation of cytosolic calcium ion concentration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

cellular response to tumor necrosis factor

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

human ageing

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

cellular calcium ion homeostasis

IGI

1 reference

14 February 2019

Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

IGI

response to heat

1 reference

14 February 2019

Arthritic calcitonin/alpha calcitonin gene-related peptide knockout mice have reduced nociceptive hypersensitivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

negative regulation of nervous system process

1 reference

24 April 2018

Elevated sympathetic nervous activity in mice deficient in alphaCGRP

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

positive regulation of ossification

1 reference

24 April 2018

Decreased bone formation and osteopenia in mice lacking alpha-calcitonin gene-related peptide

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

regulation of heart rate

1 reference

24 April 2018

Elevated sympathetic nervous activity in mice deficient in alphaCGRP

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

detection of temperature stimulus involved in sensory perception of pain

1 reference

14 February 2019

Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

negative regulation of ossification

1 reference

14 February 2019

Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

regulation of blood pressure

1 reference

24 April 2018

Mice lacking alpha-calcitonin gene-related peptide exhibit normal cardiovascular regulation and neuromuscular development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

response to pain

1 reference

14 February 2019

Modulation of morphine analgesia in alphaCGRP mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure

1 reference

14 February 2019

Elevated sympathetic nervous activity in mice deficient in alphaCGRP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

feeding behavior

1 reference

14 February 2019

Peripherally administered calcitonin gene-related peptide decreases food intake in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

nervous system process involved in regulation of systemic arterial blood pressure

1 reference

14 February 2019

Increased blood pressure in alpha-calcitonin gene-related peptide/calcitonin gene knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

sperm capacitation

1 reference

14 February 2019

Calcitonin acts as a first messenger to regulate adenylyl cyclase/cAMP and mammalian sperm function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

neuropeptide signaling pathway

1 reference

14 February 2019

Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

negative regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

activation of protein kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

embryo implantation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

negative regulation of bone resorption

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

negative regulation of blood pressure

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

ISO

24 April 2018

Increased blood pressure in alpha-calcitonin gene-related peptide/calcitonin gene knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

24 April 2018

Increased blood pressure in alpha-calcitonin gene-related peptide/calcitonin gene knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

24 April 2018

Elevated sympathetic nervous activity in mice deficient in alphaCGRP

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

24 April 2018

Calcitonin gene-related peptide protects against hypertension-induced heart and kidney damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=P70160&geneProductId=UniProtKB:P70160

negative regulation of smooth muscle contraction

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Inhibitory effect of calcitonin gene-related peptide on myometrial contractility is diminished at parturition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

adenylate cyclase-activating G protein-coupled receptor signaling pathway

Calcitonin gene-related peptide (CGRP) in the developing mouse limb

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

negative regulation of blood pressure

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

ISO

14 February 2019

Increased blood pressure in alpha-calcitonin gene-related peptide/calcitonin gene knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Calcitonin gene-related peptide protects against hypertension-induced heart and kidney damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

Increased blood pressure in alpha-calcitonin gene-related peptide/calcitonin gene knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

regulation of cytosolic calcium ion concentration

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70160

has part(s)

Calcitonin peptide-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P70160

Calcitonin, conserved site

1 reference

InterPro Release 71.0