Pages that link to "Q33957484"
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The following pages link to Structural Insight into the Aromatic Amino Acid Hydroxylases and Their Disease-Related Mutant Forms (Q33957484):
Displaying 50 items.
- Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk (Q24338261) (← links)
- A new model for allosteric regulation of phenylalanine hydroxylase: implications for disease and therapeutics (Q24617497) (← links)
- Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates (Q27639328) (← links)
- Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation (Q27639386) (← links)
- Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis (Q27662396) (← links)
- An additional substrate binding site in a bacterial phenylalanine hydroxylase (Q27679109) (← links)
- Chronic ketamine administration modulates midbrain dopamine system in mice (Q28482530) (← links)
- A synopsis on the role of tyrosine hydroxylase in Parkinson's disease (Q28830946) (← links)
- Deamidations in recombinant human phenylalanine hydroxylase. Identification of labile asparagine residues and functional characterization of Asn --> Asp mutant forms (Q30884168) (← links)
- Essential role of the N-terminal autoregulatory sequence in the regulation of phenylalanine hydroxylase (Q31864299) (← links)
- A comparison of kinetic and regulatory properties of the tetrameric and dimeric forms of wild-type and Thr427-->Pro mutant human phenylalanine hydroxylase: contribution of the flexible hinge region Asp425-Gln429 to the tetramerization and cooperativ (Q31944578) (← links)
- The 2-His-1-carboxylate facial triad: a versatile platform for dioxygen activation by mononuclear non-heme iron(II) enzymes. (Q33212392) (← links)
- Effect of the glucocorticoid receptor antagonist RU486 on MK-801 induced behavioural sensitisation (Q33590375) (← links)
- Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue (Q33826772) (← links)
- Catecholamine biosynthesis and physiological regulation in neuroendocrine cells (Q33848376) (← links)
- Polymorphisms in genes implicated in dopamine, serotonin and noradrenalin metabolism suggest association with cerebrospinal fluid monoamine metabolite concentrations in psychosis (Q34009349) (← links)
- Combining structural genomics and enzymology: completing the picture in metabolic pathways and enzyme active sites (Q34103432) (← links)
- Human tyrosine hydroxylase natural allelic variation: influence on autonomic function and hypertension (Q34435146) (← links)
- A conserved acidic residue in phenylalanine hydroxylase contributes to cofactor affinity and catalysis (Q34463948) (← links)
- Phenylalanine hydroxylase misfolding and pharmacological chaperones. (Q34556955) (← links)
- The ins and outs of ring-cleaving dioxygenases. (Q36539821) (← links)
- Loss of function in phenylketonuria is caused by impaired molecular motions and conformational instability (Q36744649) (← links)
- Electronic structure, ionization potential, and electron affinity of the enzyme cofactor (6R)-5,6,7,8-tetrahydrobiopterin in the gas phase, solution, and protein environments (Q36869608) (← links)
- Adrenergic polymorphism and the human stress response (Q37344590) (← links)
- No Evidence for Association between Tyrosine Hydroxylase Gene Val81Met Polymorphism and Susceptibility to Tardive Dyskinesia in Schizophrenia (Q37484079) (← links)
- The G46S-hPAH mutant protein: A model to study the rescue of aggregation-prone PKU mutations by chaperones (Q37922933) (← links)
- Phenylalanine hydroxylase: function, structure, and regulation. (Q38086186) (← links)
- Structural characterization of the N-terminal autoregulatory sequence of phenylalanine hydroxylase (Q38270181) (← links)
- Substituting Tyr138 in the active site loop of human phenylalanine hydroxylase affects catalysis and substrate activation. (Q38691976) (← links)
- Divergence in enzyme regulation between Caenorhabditis elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine (Q39753999) (← links)
- Phenylketonuria: genotype-phenotype correlations based on expression analysis of structural and functional mutations in PAH. (Q40661598) (← links)
- Reduction of ferric haemoproteins by tetrahydropterins: a kinetic study (Q40678941) (← links)
- A Novel Variant in the PAH Gene Causing Phenylketonuria in an Iranian Pedigree (Q40957676) (← links)
- Structural and stability effects of phosphorylation: Localized structural changes in phenylalanine hydroxylase (Q41875226) (← links)
- Predicted effects of missense mutations on native-state stability account for phenotypic outcome in phenylketonuria, a paradigm of misfolding diseases (Q42036836) (← links)
- Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation (Q42104266) (← links)
- Structural features of the regulatory ACT domain of phenylalanine hydroxylase (Q42628666) (← links)
- Identification of Phenylalanine 3-Hydroxylase for meta-Tyrosine Biosynthesis (Q42758377) (← links)
- Iron binding effects on the kinetic stability and unfolding energetics of a thermophilic phenylalanine hydroxylase from Chloroflexus aurantiacus (Q43026142) (← links)
- The effect of substrate, dihydrobiopterin, and dopamine on the EPR spectroscopic properties and the midpoint potential of the catalytic iron in recombinant human phenylalanine hydroxylase (Q43574533) (← links)
- Conjugation of phenylalanine hydroxylase with polyubiquitin chains catalysed by rat liver enzymes. (Q43643315) (← links)
- Ubiquitination of soluble and membrane-bound tyrosine hydroxylase and degradation of the soluble form (Q43902847) (← links)
- Phosphorylation and mutations of Ser(16) in human phenylalanine hydroxylase. Kinetic and structural effects (Q44107294) (← links)
- Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase (Q44358666) (← links)
- Probing cofactor specificity in phenylalanine hydroxylase by molecular dynamics simulations (Q44439495) (← links)
- Role of the second coordination sphere residue tyrosine 179 in substrate affinity and catalytic activity of phenylalanine hydroxylase (Q44785751) (← links)
- Probing the role of crystallographically defined/predicted hinge-bending regions in the substrate-induced global conformational transition and catalytic activation of human phenylalanine hydroxylase by single-site mutagenesis (Q44827080) (← links)
- Different stabilities and denaturation pathways for structurally related aromatic amino acid hydroxylases (Q44889817) (← links)
- Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins (Q45059176) (← links)
- Rescuing proteins of low kinetic stability by chaperones and natural ligands phenylketonuria, a case study (Q46136957) (← links)