Pages that link to "Q24295587"
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The following pages link to Full-length human glutaminase in complex with an allosteric inhibitor (Q24295587):
Displaying 50 items.
- Glutaminase (Q21103149) (← links)
- Links between metabolism and cancer (Q24626229) (← links)
- Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies (Q26823118) (← links)
- Rho GTPases and their roles in cancer metabolism (Q27003967) (← links)
- Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism (Q27678762) (← links)
- Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor (Q27679516) (← links)
- Structural Basis for the Active Site Inhibition Mechanism of Human Kidney-Type Glutaminase (KGA) (Q27681427) (← links)
- Design and evaluation of novel glutaminase inhibitors (Q27704265) (← links)
- Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells (Q28504783) (← links)
- Mechanistic Basis of Glutaminase Activation: A KEY ENZYME THAT PROMOTES GLUTAMINE METABOLISM IN CANCER CELLS (Q30391992) (← links)
- Serial deletion reveals structural basis and stability for the core enzyme activity of human glutaminase 1 isoforms: relevance to excitotoxic neurodegeneration (Q33587667) (← links)
- In SilicoModel-driven Assessment of the Effects of Brain-derived Neurotrophic Factor Deficiency on Glutamate and Gamma-Aminobutyric Acid: Implications for Understanding Schizophrenia Pathophysiology. (Q33662831) (← links)
- A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway (Q33709577) (← links)
- From Krebs to clinic: glutamine metabolism to cancer therapy. (Q33834498) (← links)
- Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors (Q33889353) (← links)
- Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia-cell cycle dual reporter (Q34119948) (← links)
- Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells (Q34227609) (← links)
- Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition (Q34691457) (← links)
- Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention (Q34927039) (← links)
- Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells (Q34985491) (← links)
- MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism (Q35669189) (← links)
- Effect of lysine to alanine mutations on the phosphate activation and BPTES inhibition of glutaminase (Q35738138) (← links)
- Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. (Q35836097) (← links)
- Comparative enzymology of (2S,4R)4-fluoroglutamine and (2S,4R)4-fluoroglutamate. (Q36074804) (← links)
- Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia. (Q36166888) (← links)
- Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors. (Q36517216) (← links)
- Reduction of lattice disorder in protein crystals by high-pressure cryocooling. (Q36604229) (← links)
- Inhibition of mitochondrial glutaminase activity reverses acquired erlotinib resistance in non-small cell lung cancer (Q36729484) (← links)
- Dibenzophenanthridines as inhibitors of glutaminase C and cancer cell proliferation. (Q36749597) (← links)
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. (Q36850905) (← links)
- Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome (Q36991517) (← links)
- Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer (Q37247525) (← links)
- Structural basis for exploring the allosteric inhibition of human kidney type glutaminase (Q37628958) (← links)
- Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes (Q37684619) (← links)
- Glutamine deprivation plus BPTES alters etoposide- and cisplatin-induced apoptosis in triple negative breast cancer cells (Q37688120) (← links)
- Glutaminase regulation in cancer cells: a druggable chain of events. (Q37707215) (← links)
- Therapeutic strategies impacting cancer cell glutamine metabolism (Q38139096) (← links)
- Stress eating and tuning out: cancer cells re-wire metabolism to counter stress (Q38149940) (← links)
- Harnessing allostery: a novel approach to drug discovery (Q38211688) (← links)
- Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy (Q38260557) (← links)
- Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach (Q38592248) (← links)
- A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis (Q38767151) (← links)
- Computational Model Predicts the Effects of Targeting Cellular Metabolism in Pancreatic Cancer (Q38817911) (← links)
- Tumour-Derived Glutamate: Linking Aberrant Cancer Cell Metabolism to Peripheral Sensory Pain Pathways (Q38828988) (← links)
- Small-molecule binding sites to explore protein-protein interactions in the cancer proteome (Q39565398) (← links)
- T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions (Q41943060) (← links)
- Allosteric Glutaminase Inhibitors Based on a 1,4-Di(5-amino-1,3,4-thiadiazol-2-yl)butane Scaffold. (Q42239514) (← links)
- Balancing redox stress: anchorage-independent growth requires reductive carboxylation (Q42320519) (← links)
- Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition (Q42364281) (← links)
- The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats. (Q46214542) (← links)