Pages that link to "Q70827252"
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The following pages link to Kim L.R. Brouwer (Q70827252):
Displaying 50 items.
- Lack of effect of ondansetron on the pharmacokinetics and analgesic effects of morphine and metabolites after single-dose morphine administration in healthy volunteers (Q28363531) (← links)
- Membrane transporters in drug development (Q29616802) (← links)
- Hepatobiliary disposition of troglitazone and metabolites in rat and human sandwich-cultured hepatocytes: use of Monte Carlo simulations to assess the impact of changes in biliary excretion on troglitazone sulfate accumulation. (Q33574904) (← links)
- Identification of hepatic phospholipidosis inducers in sandwich-cultured rat hepatocytes, a physiologically relevant model, reveals altered basolateral uptake and biliary excretion of anionic probe substrates (Q33686976) (← links)
- Population pharmacokinetics of azithromycin in whole blood, peripheral blood mononuclear cells, and polymorphonuclear cells in healthy adults. (Q33689718) (← links)
- Population Pharmacokinetics of Morphine in Patients With Nonalcoholic Steatohepatitis (NASH) and Healthy Adults. (Q33729768) (← links)
- Hepatocellular exposure of troglitazone metabolites in rat sandwich-cultured hepatocytes lacking Bcrp and Mrp2: interplay between formation and excretion. (Q33742713) (← links)
- Key Role for the 12-Hydroxy Group in the Negative Ion Fragmentation of Unconjugated C24 Bile Acids. (Q33906607) (← links)
- Mechanistic Modeling Reveals the Critical Knowledge Gaps in Bile Acid-Mediated DILI (Q33994553) (← links)
- Sulindac and its metabolites inhibit multiple transport proteins in rat and human hepatocytes. (Q34035243) (← links)
- Role of multidrug resistance-associated protein 4 in the basolateral efflux of hepatically derived enalaprilat. (Q34125053) (← links)
- Medication use and medical comorbidity in patients with chronic hepatitis C from a US commercial claims database: high utilization of drugs with interaction potential. (Q34143327) (← links)
- Perspectives on a pharmacokinetics legend: C versus T (contributions over time). (Q34349207) (← links)
- Novel mechanism of impaired function of organic anion-transporting polypeptide 1B3 in human hepatocytes: post-translational regulation of OATP1B3 by protein kinase C activation. (Q34360004) (← links)
- Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes. (Q34377815) (← links)
- Exploring BSEP inhibition-mediated toxicity with a mechanistic model of drug-induced liver injury. (Q34471194) (← links)
- Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes. (Q34701840) (← links)
- Decreased hepatic breast cancer resistance protein expression and function in multidrug resistance-associated protein 2-deficient (TR⁻) rats (Q34702620) (← links)
- Mechanisms underlying differences in systemic exposure of structurally similar active metabolites: comparison of two preclinical hepatic models. (Q34868070) (← links)
- Sandwich-cultured hepatocytes: an in vitro model to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity. (Q34990717) (← links)
- Use of cassette dosing in sandwich-cultured rat and human hepatocytes to identify drugs that inhibit bile acid transport. (Q35086229) (← links)
- Evaluation of (99m)technetium-mebrofenin and (99m)technetium-sestamibi as specific probes for hepatic transport protein function in rat and human hepatocytes (Q35086354) (← links)
- Pharmacokinetics and bioavailability of zidovudine and its glucuronidated metabolite in patients with human immunodeficiency virus infection and hepatic disease (AIDS Clinical Trials Group protocol 062). (Q35120894) (← links)
- Toward predicting drug-induced liver injury: parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors (Q35531766) (← links)
- Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury (Q35531814) (← links)
- Influence of seeding density and extracellular matrix on bile Acid transport and mrp4 expression in sandwich-cultured mouse hepatocytes. (Q35607383) (← links)
- A semiphysiologically based pharmacokinetic modeling approach to predict the dose-exposure relationship of an antiparasitic prodrug/active metabolite pair. (Q35647136) (← links)
- Fluconazole population pharmacokinetics and dosing for prevention and treatment of invasive Candidiasis in children supported with extracorporeal membrane oxygenation. (Q35746253) (← links)
- Systems pharmacology modeling predicts delayed presentation and species differences in bile acid-mediated troglitazone hepatotoxicity (Q35781894) (← links)
- The complexities of hepatic drug transport: current knowledge and emerging concepts. (Q35793721) (← links)
- Modelling the cardiovascular effects of ephedrine (Q35826107) (← links)
- Determination of the biliary excretion of piperacillin in humans using a novel method. (Q35827777) (← links)
- Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitis (Q35842935) (← links)
- Roles of P-glycoprotein, Bcrp, and Mrp2 in biliary excretion of spiramycin in mice. (Q36094800) (← links)
- Pharmacokinetics and safety of fluconazole in young infants supported with extracorporeal membrane oxygenation. (Q36240580) (← links)
- Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis (Q36893921) (← links)
- Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury. (Q36972804) (← links)
- Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes. (Q37027044) (← links)
- A perspective on efflux transport proteins in the liver (Q37050337) (← links)
- Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers. (Q37081457) (← links)
- Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in freshly isolated rat hepatocytes (Q37103935) (← links)
- Influence of drug transport proteins on the pharmacokinetics and drug interactions of HIV protease inhibitors. (Q37113947) (← links)
- Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: role of multidrug resistance-associated protein 2 (Abcc2). (Q37139671) (← links)
- Use of sandwich-cultured human hepatocytes to predict biliary clearance of angiotensin II receptor blockers and HMG-CoA reductase inhibitors. (Q37188002) (← links)
- Determination of intracellular unbound concentrations and subcellular localization of drugs in rat sandwich-cultured hepatocytes compared with liver tissue. (Q37251993) (← links)
- Sex-dependent disposition of acetaminophen sulfate and glucuronide in the in situ perfused mouse liver. (Q37311636) (← links)
- Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes (Q37331801) (← links)
- Hepatic basolateral efflux contributes significantly to rosuvastatin disposition II: characterization of hepatic elimination by basolateral, biliary, and metabolic clearance pathways in rat isolated perfused liver. (Q37331821) (← links)
- Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors. (Q37564187) (← links)
- In vivo alterations in drug metabolism and transport pathways in patients with chronic kidney diseases. (Q37622756) (← links)