Pages that link to "Q57269958"
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The following pages link to Flt3-dependent transformation by inactivating c-Cbl mutations in AML (Q57269958):
Displaying 50 items.
- Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function (Q24314826) (← links)
- Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms (Q24595117) (← links)
- Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases (Q26852269) (← links)
- RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis (Q26853207) (← links)
- Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1 (Q27687464) (← links)
- Recent advances in diagnosis, molecular pathology and therapy of chronic myelomonocytic leukaemia (Q28307278) (← links)
- Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders (Q28307750) (← links)
- CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases (Q33528991) (← links)
- Ubiquitination and degradation of the thrombopoietin receptor c-Mpl. (Q33677470) (← links)
- The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia (Q33796552) (← links)
- Cbl and human myeloid neoplasms: the Cbl oncogene comes of age. (Q33925815) (← links)
- Heterozygous germline mutations in the CBL tumor-suppressor gene cause a Noonan syndrome-like phenotype. (Q34050931) (← links)
- Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells (Q34136434) (← links)
- Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism (Q34186690) (← links)
- Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling. (Q34541947) (← links)
- Mutations of e3 ubiquitin ligase cbl family members constitute a novel common pathogenic lesion in myeloid malignancies. (Q34578265) (← links)
- CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia. (Q35030952) (← links)
- The role of the c-Met pathway in lung cancer and the potential for targeted therapy (Q35146937) (← links)
- Molecular pathways: cbl proteins in tumorigenesis and antitumor immunity-opportunities for cancer treatment (Q35463260) (← links)
- Balancing Protein Stability and Activity in Cancer: A New Approach for Identifying Driver Mutations Affecting CBL Ubiquitin Ligase Activation (Q35871171) (← links)
- Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia (Q35901705) (← links)
- p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis. (Q35953378) (← links)
- An E3 ubiquitin ligase: c-Cbl: a new therapeutic target of lung cancer (Q36060419) (← links)
- Deleterious c-Cbl Exon Skipping Contributes to Human Glioma. (Q36480205) (← links)
- Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells (Q36508969) (← links)
- UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO. (Q36642902) (← links)
- c-Cbl expression levels regulate the functional responses of human central and effector memory CD4 T cells (Q36787601) (← links)
- Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl. (Q36843787) (← links)
- SH2B3 (LNK) mutations from myeloproliferative neoplasms patients have mild loss of function against wild type JAK2 and JAK2 V617F. (Q36901651) (← links)
- Casitas B-cell lymphoma mutation in childhood T-cell acute lymphoblastic leukemia (Q36958309) (← links)
- Cooperating gene mutations in acute myeloid leukemia: a review of the literature. (Q37089717) (← links)
- The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents (Q37141899) (← links)
- Derailed endocytosis: an emerging feature of cancer (Q37307506) (← links)
- Mutations in CBL occur frequently in juvenile myelomonocytic leukemia (Q37334614) (← links)
- Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells (Q37565024) (← links)
- The challenge of risk stratification in acute myeloid leukemia with normal karyotype (Q37671778) (← links)
- Unraveling the Molecular Pathophysiology of Myelodysplastic Syndromes (Q37671806) (← links)
- Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms (Q37710951) (← links)
- Drug resistance in mutant FLT3-positive AML. (Q37771863) (← links)
- Molecular diagnosis of acute myeloid leukemia (Q37809866) (← links)
- JAK2V617F and beyond: role of genetics and aberrant signaling in the pathogenesis of myeloproliferative neoplasms (Q37810100) (← links)
- Feedback regulation of EGFR signalling: decision making by early and delayed loops. (Q37831109) (← links)
- Differential signaling of Flt3 activating mutations in acute myeloid leukemia: a working model (Q37848133) (← links)
- Current findings for recurring mutations in acute myeloid leukemia (Q37932085) (← links)
- Endocytosis and signaling: cell logistics shape the eukaryotic cell plan (Q37980726) (← links)
- Heterogeneity of molecular markers in chronic myelomonocytic leukemia: a disease associated with several gene alterations. (Q37993420) (← links)
- Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications (Q38021448) (← links)
- Genetic and epigenetic alterations of myeloproliferative disorders (Q38066786) (← links)
- FLT3 inhibitors for acute myeloid leukemia: a review of their efficacy and mechanisms of resistance (Q38101284) (← links)
- Cbl-family proteins as regulators of cytoskeleton-dependent phenomena (Q38112644) (← links)