Pages that link to "Q50651862"
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The following pages link to The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a'-go-go-related gene (hERG) K+ channel (Q50651862):
Displaying 50 items.
- Insight into the molecular interaction between the cyclic nucleotide-binding homology domain and the eag domain of the hERG channel (Q24299208) (← links)
- A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels (Q24655800) (← links)
- The S4–S5 Linker Acts as a Signal Integrator for hERG K+ Channel Activation and Deactivation Gating (Q27677437) (← links)
- The role of distal S6 hydrophobic residues in the voltage-dependent gating of CaV2.3 channels (Q27865194) (← links)
- Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating (Q30474096) (← links)
- Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel (Q30499333) (← links)
- Proline scan of the HERG channel S6 helix reveals the location of the intracellular pore gate. (Q33634079) (← links)
- Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na V 1.7 produce distinct pain disorders (Q33875626) (← links)
- Mutations within the S4-S5 linker alter voltage sensor constraints in hERG K+ channels (Q34250545) (← links)
- The Eag domain regulates the voltage-dependent inactivation of rat Eag1 K+ channels (Q34379526) (← links)
- KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain. (Q34452725) (← links)
- Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating (Q34569783) (← links)
- Demonstration of physical proximity between the N terminus and the S4-S5 linker of the human ether-a-go-go-related gene (hERG) potassium channel (Q34998277) (← links)
- Double mutant cycle analysis identified a critical leucine residue in the IIS4S5 linker for the activation of the Ca(V)2.3 calcium channel (Q35144814) (← links)
- Conservation analysis of residues in the S4-S5 linker and the terminal part of the S5-P-S6 pore modulus in Kv and HCN channels: flexible determinants for the electromechanical coupling. (Q35422054) (← links)
- C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation (Q35745902) (← links)
- Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. (Q35963083) (← links)
- Opposite Effects of the S4-S5 Linker and PIP(2) on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels (Q36076020) (← links)
- Coupling of voltage-sensors to the channel pore: a comparative view (Q36121859) (← links)
- Structural changes during HCN channel gating defined by high affinity metal bridges. (Q36209612) (← links)
- Reversal of HCN channel voltage dependence via bridging of the S4-S5 linker and Post-S6. (Q36295815) (← links)
- Cold-aggravated pain in humans caused by a hyperactive NaV1.9 channel mutant (Q36392068) (← links)
- Perspectives on: conformational coupling in ion channels: thermodynamics of electromechanical coupling in voltage-gated ion channels. (Q36446427) (← links)
- Identification of functionally critical residues in the channel domain of inositol trisphosphate receptors (Q36481838) (← links)
- Allosteric coupling between proximal C-terminus and selectivity filter is facilitated by the movement of transmembrane segment 4 in TREK-2 channel (Q36583087) (← links)
- Structural determinants of skeletal muscle ryanodine receptor gating (Q36647234) (← links)
- hERG gating microdomains defined by S6 mutagenesis and molecular modeling. (Q36946670) (← links)
- Dynamic coupling of voltage sensor and gate involved in closed-state inactivation of kv4.2 channels (Q37089286) (← links)
- Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels. (Q37121999) (← links)
- Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels (Q37209213) (← links)
- Transfer of rolf S3-S4 linker to HERG eliminates activation gating but spares inactivation (Q37359431) (← links)
- The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking. (Q37632853) (← links)
- HCN-related channelopathies. (Q37705120) (← links)
- Aromatic-aromatic interactions between residues in KCa3.1 pore helix and S5 transmembrane segment control the channel gating process (Q37727041) (← links)
- Linking structure to function: Recent lessons from inositol 1,4,5-trisphosphate receptor mutagenesis (Q37761443) (← links)
- Cytoplasmic domains and voltage-dependent potassium channel gating. (Q37999317) (← links)
- HERG potassium channel regulation by the N-terminal eag domain (Q38004348) (← links)
- Voltage-dependent gating of HERG potassium channels (Q38010173) (← links)
- Mechanism of electromechanical coupling in voltage-gated potassium channels (Q38044382) (← links)
- Being flexible: the voltage-controllable activation gate of kv channels. (Q38044898) (← links)
- Molecular Basis of Cardiac Delayed Rectifier Potassium Channel Function and Pharmacology (Q38854244) (← links)
- Molecular Pathophysiology of Congenital Long QT Syndrome (Q38997049) (← links)
- Components of gating charge movement and S4 voltage-sensor exposure during activation of hERG channels (Q39182563) (← links)
- Activation of Slo2.1 channels by niflumic acid (Q39288976) (← links)
- Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains. (Q39372227) (← links)
- The hERG K+ channel S4 domain L532P mutation: Characterization at 37°C (Q39503158) (← links)
- Pathogenic effects of a novel mutation (c.664_681del) in KCNQ4 channels associated with auditory pathology (Q39657036) (← links)
- Modulation of HERG gating by a charge cluster in the N-terminal proximal domain. (Q40228198) (← links)
- A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel. (Q40383649) (← links)
- Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation (Q41045858) (← links)