Pages that link to "Q40841014"

The following pages link to Enhanced gamma-carboxylation of recombinant factor X using a chimeric construct containing the prothrombin propeptide (Q40841014):

Displaying 30 items.

• Regulated cleavage of prothrombin by prothrombinase: repositioning a cleavage site reveals the unique kinetic behavior of the action of prothrombinase on its compound substrate (Q33581285) (← links)
• Ratcheting of the substrate from the zymogen to proteinase conformations directs the sequential cleavage of prothrombin by prothrombinase (Q33895760) (← links)
• The N-terminal epidermal growth factor-like domain in factor IX and factor X represents an important recognition motif for binding to tissue factor (Q34103306) (← links)
• The vitamin K cycle. (Q34443182) (← links)
• Restricted active site docking by enzyme-bound substrate enforces the ordered cleavage of prothrombin by prothrombinase (Q36538488) (← links)
• Post-translational modifications in the context of therapeutic proteins (Q36620451) (← links)
• Characterization of vitamin K-dependent carboxylase mutations that cause bleeding and nonbleeding disorders (Q36800446) (← links)
• Industrial production of clotting factors: Challenges of expression, and choice of host cells (Q38534584) (← links)
• A cluster of basic amino acids in the factor X serine protease mediates surface attachment of adenovirus/FX complexes (Q38631798) (← links)
• Functional expression of the human coagulation factor IX using heterologous signal peptide and propeptide sequences in mammalian cell line. (Q38860655) (← links)
• Biological Insights into Therapeutic Protein Modifications throughout Trafficking and Their Biopharmaceutical Applications (Q39149359) (← links)
• Stable and high-level production of recombinant Factor IX in human hepatic cell line (Q39490991) (← links)
• The conformational switch from the factor X zymogen to protease state mediates exosite expression and prothrombinase assembly (Q39627929) (← links)
• Galectin 3-binding protein is a potential contaminant of recombinantly produced factor IX. (Q40059443) (← links)
• Binding of substrate in two conformations to human prothrombinase drives consecutive cleavage at two sites in prothrombin (Q40502059) (← links)
• Prothrombinase assembly and S1 site occupation restore the catalytic activity of FXa impaired by mutation at the sodium-binding site (Q40714392) (← links)
• Nematode anticoagulant protein c2 reveals a site on factor Xa that is important for macromolecular substrate binding to human prothrombinase (Q40732079) (← links)
• Engineered factor Xa variants retain procoagulant activity independent of direct factor Xa inhibitors. (Q41125977) (← links)
• Fate of membrane-bound reactants and products during the activation of human prothrombin by prothrombinase (Q41819023) (← links)
• The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo (Q42791749) (← links)
• Binding of the factor IX gamma-carboxyglutamic acid domain to the vitamin K-dependent gamma-glutamyl carboxylase active site induces an allosteric effect that may ensure processive carboxylation and regulate the release of carboxylated product (Q44683481) (← links)
• Thrombin-activable factor X re-establishes an intrinsic amplification in tenase-deficient plasmas. (Q45887421) (← links)
• Effect of propeptide amino acid substitution in γ-carboxylation, activity and expression of recombinant human coagulation factor IX. (Q46271852) (← links)
• The elusive role of the potential factor X cation-binding exosite-1 in substrate and inhibitor interactions. (Q47418397) (← links)
• Secretion of wild-type factor IX upon readthrough over F9 pre-peptide nonsense mutations causing hemophilia B. (Q49503585) (← links)
• Formation of factors IXa and Xa by the extrinsic pathway: differential regulation by tissue factor pathway inhibitor and antithrombin III. (Q51037137) (← links)
• A rapid pro-hemostatic approach to overcome direct oral anticoagulants (Q51618025) (← links)
• Truncated gamma-glutamyl carboxylase in rambouillet sheep. (Q54591854) (← links)
• Gene-based FVIIa prophylaxis modulates the spontaneous bleeding phenotype of hemophilia A rats (Q61804717) (← links)
• A candidate activation pathway for coagulation factor VII (Q90182302) (← links)