Pages that link to "Q40758704"

The following pages link to A manual method for applying the Hansch approach to drug design (Q40758704):

Displaying 48 items.

• Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4'-phenyl)-phenethyl) analogues of 8-CAC (Q24680272) (← links)
• 1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI) (Q27634251) (← links)
• Design, synthesis, and activity of a series of arylpyrid-3-ylmethanones as type I positive allosteric modulators of α7 nicotinic acetylcholine receptors (Q30570721) (← links)
• Peptoids: a modular approach to drug discovery. (Q33191665) (← links)
• Synthesis, in vitro and in vivo cytotoxicity of 6,7-diaryl-2,3,8,8a-tetrahydroindolizin-5(1H)-ones (Q33290069) (← links)
• Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1 (Q33644620) (← links)
• Structure-activity relationship of cinnamaldehyde analogs as inhibitors of AI-2 based quorum sensing and their effect on virulence of Vibrio spp (Q33797898) (← links)
• Synthesis and evaluation of indatraline-based inhibitors for trypanothione reductase (Q33806133) (← links)
• Isoform-specific prolongation of Kv7 (KCNQ) potassium channel opening mediated by new molecular determinants for drug-channel interactions (Q34107486) (← links)
• Using matched molecular series as a predictive tool to optimize biological activity (Q34408629) (← links)
• Selective human adenosine A3 antagonists based on pyrido[2,1-f]purine-2,4-diones: novel features of hA3 antagonist binding. (Q34713557) (← links)
• The cytotoxic properties and preferential toxicity to tumour cells displayed by some 2,4-bis(benzylidene)-8-methyl-8-azabicyclo[3.2.1] octan-3-ones and 3,5-bis(benzylidene)-1-methyl-4-piperidones (Q35748094) (← links)
• Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. (Q36042441) (← links)
• Discovery of novel 1,2,3-triazole derivatives as anticancer agents using QSAR and in silico structural modification (Q36234222) (← links)
• Structure-activity relationships and pharmacophore model of a noncompetitive pyrazoline containing class of GluN2C/GluN2D selective antagonists (Q36276693) (← links)
• Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs (Q36477032) (← links)
• Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice (Q37352712) (← links)
• 1,5-diaryl-3-oxo-1,4-pentadienes: a case for antineoplastics with multiple targets (Q37515723) (← links)
• Synthesis, Modelling, and Anticonvulsant Studies of New Quinazolines Showing Three Highly Active Compounds with Low Toxicity and High Affinity to the GABA-A Receptor. (Q38765628) (← links)
• Rational drug design, synthesis and biological evaluation of dihydrofolate reductase inhibitors as antituberculosis agents (Q38997068) (← links)
• Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295. (Q39157688) (← links)
• Lipophilicity and drug activity (Q39857371) (← links)
• Developments in histamine H1-receptor agonists (Q40465197) (← links)
• Synthesis of some benzimidazole derivatives endowed with 1,2,3-triazole as potential inhibitors of hepatitis C virus. (Q40711348) (← links)
• Dihydropyridine neuropeptide Y Y(1) receptor antagonists (Q40754187) (← links)
• Structure-Affinity Relationships and Structure-Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A3 Receptor Antagonists (Q41722014) (← links)
• Topliss Batchwise Schemes Reviewed in the Era of Open Data Reveal Significant Differences between Enzymes and Membrane Receptors (Q42692196) (← links)
• New groups of antimycobacterial agents: 6-chloro-3-phenyl-4-thioxo-2H-1,3-benzoxazine-2(3H)-ones and 6-chloro-3-phenyl-2H-1,3-benzoxazine-2,4(3H)-dithiones (Q43506500) (← links)
• Synthesis, structure investigations, and antimicrobial activity of selected s-trans-6-aryl-4-isopropyl-2-[2-[(E)-1-phenylalkylidene]-(E)-hydrazino]-1,4-dihydropyrimidine hydrochlorides (Q43861608) (← links)
• Potential tuberculostatic agents. Topliss application on benzoic acid [(5-nitro-thiophen-2-yl)-methylene]-hydrazide series (Q43869081) (← links)
• On the relationship between the substitution pattern of thiobenzanilides and their antimycobacterial activity. (Q44183565) (← links)
• Cytotoxic and topographical properties of 6-arylidene-2-dimethylaminomethylcyclohexanone hydrochlorides and related compounds (Q44940401) (← links)
• Correlation of activity of 2-(X-benzyloxy)-4,6-dimethoxyacetophenones with topological indices and with the Hansch equation (Q46333243) (← links)
• Structure-activity relationships of phenylpropanoids as antifeedants for the pine weevil Hylobius abietis (Q46725032) (← links)
• An exploration of the structure-activity relationships of 4-aminoquinolines: novel antimalarials with activity in-vivo (Q48033243) (← links)
• Synthesis and Biochemical Evaluation ofN-(4-Phenylthiazol-2-yl)benzenesulfonamides as High-Affinity Inhibitors of Kynurenine 3-Hydroxylase (Q48561687) (← links)
• Effects of 1,3,5-triphenyl-4,5-dihydro-1H-pyrazole derivatives on cell-cycle and apoptosis in human acute leukemia cell lines. (Q52793168) (← links)
• Design, synthesis and biological evaluation of pyridine-phenylpiperazines: a novel series of potent and selective alpha1a-adrenergic receptor antagonist. (Q54398761) (← links)
• Cytotoxic 1,3-diarylidene-2-tetralones and related compounds (Q56786453) (← links)
• Allosteric modulation of the farnesoid X receptor by a small molecule (Q57120289) (← links)
• Benzenesulfonamide derivatives of 2-substituted 4H-3,1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease (Q58115545) (← links)
• A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism (Q58488814) (← links)
• Synthesis of α-Aryl-Substituted and Conformationally Restricted Fosmidomycin Analogues as Promising Antimalarials (Q63363648) (← links)
• Anticonvulsant properties of various acetylhydrazones, oxamoylhydrazones and semicarbazones derived from aromatic and unsaturated carbonyl compounds. (Q64976762) (← links)
• Analgesic activity of cyclic imides: 1,8-naphthalimide and 1,4,5,8-naphthalenediimide derivatives (Q74245097) (← links)
• Design, synthesis and antimycobacterial activity of cinnamide derivatives: A molecular hybridization approach (Q83535822) (← links)
• Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus (Q91897802) (← links)
• Developing RNA aptamers for potential treatment of neurological diseases (Q92624359) (← links)