Pages that link to "Q28588674"

The following pages link to Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3 (Q28588674):

Displaying 50 items.

• Presenilin 2 (Q21988969) ‎ (← links)
• A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein (Q22009982) ‎ (← links)
• Calsenilin reverses presenilin-mediated enhancement of calcium signaling (Q22254629) ‎ (← links)
• Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (Q24292400) ‎ (← links)
• Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation (Q24312000) ‎ (← links)
• Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease (Q24317439) ‎ (← links)
• Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau (Q24320124) ‎ (← links)
• Generation of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavage (Q24322944) ‎ (← links)
• Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis (Q24675701) ‎ (← links)
• Mutations in presenilin 2 and its implications in Alzheimer's disease and other dementia-associated disorders (Q26800286) ‎ (← links)
• Interaction of Alzheimer's presenilin-1 and presenilin-2 with Bcl-X(L). A potential role in modulating the threshold of cell death (Q28142036) ‎ (← links)
• Presenilin 1 protein directly interacts with Bcl-2 (Q28145902) ‎ (← links)
• Direct association of presenilin-1 with beta-catenin (Q28282616) ‎ (← links)
• Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment (Q28285327) ‎ (← links)
• Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency (Q28505078) ‎ (← links)
• Identification of caspases that cleave presenilin-1 and presenilin-2 (Q29999194) ‎ (← links)
• Structural and dynamical studies of Humanin in water and TFE/water mixture: a molecular dynamics simulation. (Q31161261) ‎ (← links)
• Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP). (Q33289346) ‎ (← links)
• Biology of presenilins as causative molecules for Alzheimer disease. (Q33653958) ‎ (← links)
• The role of cell cycle-mediated events in Alzheimer's disease (Q33723773) ‎ (← links)
• Presenilins and Alzheimer's disease: biological functions and pathogenic mechanisms (Q33835683) ‎ (← links)
• Caspases and neurodegeneration: on the cutting edge of new therapeutic approaches. (Q33873247) ‎ (← links)
• Presenilin structure, function and role in Alzheimer disease. (Q33971264) ‎ (← links)
• LDL receptor-related protein (LRP) in Alzheimer's disease: towards a unified theory of pathogenesis (Q33998653) ‎ (← links)
• Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons (Q34021637) ‎ (← links)
• Apoptosis and neurologic disease (Q34051306) ‎ (← links)
• Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease (Q34208401) ‎ (← links)
• Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease (Q35763750) ‎ (← links)
• Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically (Q35826855) ‎ (← links)
• Conserved Molecular Underpinnings and Characterization of a Role for Caveolin-1 in the Tumor Microenvironment of Mature T-Cell Lymphomas (Q35840904) ‎ (← links)
• Presenilin function and gamma-secretase activity (Q36109130) ‎ (← links)
• Increased apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin-2 mutation (N141I). (Q36273909) ‎ (← links)
• Additional evidence for an eight-transmembrane-domain topology for Caenorhabditis elegans and human presenilins (Q36510548) ‎ (← links)
• Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection (Q36526897) ‎ (← links)
• Alzheimer's presenilin 1 causes chromosome missegregation and aneuploidy (Q37218464) ‎ (← links)
• Isoenzymes of protein kinase C: differential involvement in apoptosis and pathogenesis (Q37228253) ‎ (← links)
• Presenilin 2 overexpression is associated with apoptosis in Neuro2a cells (Q37585437) ‎ (← links)
• Egr1 promotes growth and survival of prostate cancer cells. Identification of novel Egr1 target genes (Q38358220) ‎ (← links)
• Interplay of the Ca2+-binding protein DREAM with presenilin in neuronal Ca2+ signaling (Q39956189) ‎ (← links)
• Interference with splicing of Presenilin transcripts has potent dominant negative effects on Presenilin activity (Q40056954) ‎ (← links)
• The presenilin-2 loop peptide perturbs intracellular Ca2+ homeostasis and accelerates apoptosis (Q40294317) ‎ (← links)
• Mutant nicastrin protein can induce the cytochrome c release and the Bax expression (Q40515353) ‎ (← links)
• Overexpression of wild-type presenilin 2 or its familial Alzheimer's disease-associated mutant does not induce or increase susceptibility to apoptosis in different cell lines. (Q40668193) ‎ (← links)
• Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. (Q40714164) ‎ (← links)
• A loss of function mutant of the presenilin homologue SEL-12 undergoes aberrant endoproteolysis in Caenorhabditis elegans and increases abeta 42 generation in human cells (Q40851871) ‎ (← links)
• Presenilin overexpression arrests cells in the G1 phase of the cell cycle. Arrest potentiated by the Alzheimer's disease PS2(N141I)mutant (Q40944221) ‎ (← links)
• Contrasting role of presenilin-1 and presenilin-2 in neuronal differentiation in vitro. (Q40982564) ‎ (← links)
• In vivo expression of an alternatively spliced human tumor message that encodes a truncated form of cathepsin B. Subcellular distribution of the truncated enzyme in COS cells (Q41040308) ‎ (← links)
• Regulation of apoptosis by presenilin 1. (Q41048086) ‎ (← links)
• Presenilin-2 mutations modulate amplitude and kinetics of inositol 1, 4,5-trisphosphate-mediated calcium signals (Q41700856) ‎ (← links)