Axonal transport defects in Alzheimer's disease (Q38232821)

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Language	Label	Description	Also known as
English	Axonal transport defects in Alzheimer's disease	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

Axonal transport defects in Alzheimer's disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

Alzheimer's disease

0 references

object named as

Jin-Tai Yu

3

0 references

2

object named as

Lan Tan

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

author name string

Zi-Xuan Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

publication date

23 July 2014

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

Molecular Neurobiology

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

51

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

1309-1321

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

BACE1 Elevation is Involved in Amyloid Plaque Development in the Triple Transgenic Model of Alzheimer’s Disease: Differential Aβ Antibody Labeling of Early-Onset Axon Terminal Pathology

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Epigenetic mechanisms in Alzheimer's disease: implications for pathogenesis and therapy

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Endogenous GSK-3/shaggy regulates bidirectional axonal transport of the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

A peptide zipcode sufficient for anterograde transport within amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Abeta promotes Alzheimer's disease-like cytoskeleton abnormalities with consequences to APP processing in neurons

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Histone deacetylase 6 interacts with the microtubule-associated protein tau

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Acute effect of beta amyloid on synchronized spontaneous Ca2+ oscillations in cultured hippocampal networks

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Aβ Oligomers Cause Localized Ca2+Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Presenilin influences glycogen synthase kinase-3 β (GSK-3β) for kinesin-1 and dynein function during axonal transport

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Defective brain microtubule assembly in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Axonal degeneration induced by targeted expression of mutant human tau in oligodendrocytes of transgenic mice that model glial tauopathies.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Single-molecule investigation of the interference between kinesin, tau and MAP2c

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Tau binding to microtubules does not directly affect microtubule-based vesicle motility

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Interaction of tau protein with the dynactin complex

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Quantitative assessment of cortical synaptic density in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Expression of beta-amyloid induced age-dependent presynaptic and axonal changes in Drosophila.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

HDAC6 inhibitor blocks amyloid beta-induced impairment of mitochondrial transport in hippocampal neurons

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Regulation of axonal trafficking of cytochrome c oxidase IV mRNA

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Autophagy, amyloidogenesis and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Apolipoprotein E in Alzheimer's disease: an update

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Abeta exacerbates the neuronal dysfunction caused by human tau expression in a Drosophila model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Tau reduction prevents Abeta-induced defects in axonal transport.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Brain-penetrant microtubule-stabilizing compounds as potential therapeutic agents for tauopathies

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Notch signalling in adult neurons: a potential target for microtubule stabilization.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Proteasome inhibition induces stress kinase dependent transport deficits--implications for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Nebula/DSCR1 upregulation delays neurodegeneration and protects against APP-induced axonal transport defects by restoring calcineurin and GSK-3β signaling

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8810-X

21 January 2018

Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

March separate, strike together--role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coexpression of GSK-3beta corrects phenotypic aberrations of dorsal root ganglion cells, cultured from adult transgenic mice overexpressing human protein tau

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unloading kinesin transported cargoes from the tubulin track via the inflammatory c-Jun N-terminal kinase pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GSK3 beta forms a tetrameric complex with endogenous PS1-CTF/NTF and beta-catenin. Effects of the D257/D385A and FAD-linked mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global axonal transport rates are unaltered in htau mice in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial secret(ase) of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of kinesin: implications for neuronal development

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate and Amyloid β-Protein Rapidly Inhibit Fast Axonal Transport in Cultured Rat Hippocampal Neurons by Different Mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/25052480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12035-014-8810-X

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 August 2017

ResearchGate publication ID

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