Maintaining and reprogramming genomic androgen receptor activity in prostate cancer (Q38190362)

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scientific article published on March 2014

Language	Label	Description	Also known as
English	Maintaining and reprogramming genomic androgen receptor activity in prostate cancer	scientific article published on March 2014

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

1 reference

Europe PubMed Central

Maintaining and reprogramming genomic androgen receptor activity in prostate cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

prostate cancer

1 reference

based on heuristic

inferred from title

author name string

Ian G Mills

1

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

language of work or name

0 references

publication date

1 March 2014

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Nature Reviews Cancer

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

187-198

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

DNA and ribonucleotide binding characteristics of two forms of the androgen receptor from rat prostates

1 reference

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21 January 2018

Molecular mechanisms of androgen receptor-mediated gene regulation: structure-function analysis of the AF-1 domain

1 reference

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21 January 2018

Structural basis for the nuclear import of the human androgen receptor

1 reference

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21 January 2018

Abiraterone in metastatic prostate cancer without previous chemotherapy

1 reference

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21 January 2018

Increased survival with enzalutamide in prostate cancer after chemotherapy

1 reference

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21 January 2018

In vivo amplification of the androgen receptor gene and progression of human prostate cancer

1 reference

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21 January 2018

Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines

1 reference

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21 January 2018

Overcoming mutation-based resistance to antiandrogens with rational drug design

1 reference

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21 January 2018

Overexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer

1 reference

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21 January 2018

Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

1 reference

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21 January 2018

Genetic variants associated with the progression of hepatocellular carcinoma in hepatitis C Egyptian patients

1 reference

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21 January 2018

Mapping protein-DNA interactions using ChIP-sequencing.

1 reference

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21 January 2018

Integrated expression profiling and ChIP-seq analyses of the growth inhibition response program of the androgen receptor

1 reference

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21 January 2018

An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression

1 reference

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21 January 2018

The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man.

1 reference

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21 January 2018

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

1 reference

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21 January 2018

Testosterone and prolactin regulation of metabolic genes and citrate metabolism of prostate epithelial cells

1 reference

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21 January 2018

Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements

1 reference

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21 January 2018

A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.

1 reference

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21 January 2018

Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target?

1 reference

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21 January 2018

PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis

1 reference

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21 January 2018

Dual roles of PARP-1 promote cancer growth and progression

1 reference

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21 January 2018

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Induced chromosomal proximity and gene fusions in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

The genomic landscape of prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

New androgen receptor genomic targets show an interaction with the ETS1 transcription factor.

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 activation

1 reference

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21 January 2018

Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

H3K36 methylation antagonizes PRC2-mediated H3K27 methylation

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Putting the brakes on continued androgen receptor signaling in castration-resistant prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Lupus resistance is associated with marginal zone abnormalities in an NZM murine model.

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Targeting pioneering factor and hormone receptor cooperative pathways to suppress tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

FOXA1 is a key determinant of estrogen receptor function and endocrine response

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

The mutational landscape of lethal castration-resistant prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

A role for GATA-2 in transition to an aggressive phenotype in prostate cancer through modulation of key androgen-regulated genes.

1 reference

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21 January 2018

Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Prostate cancer: germline prediction for a commonly variable malignancy.

1 reference

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21 January 2018

A population-based assessment of germline HOXB13 G84E mutation and prostate cancer risk

1 reference

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21 January 2018

HOXB13 G84E mutation in Finland: population-based analysis of prostate, breast, and colorectal cancer risk

1 reference

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21 January 2018

The homeodomain protein HOXB13 regulates the cellular response to androgens

1 reference

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21 January 2018

Interleukin-6 serum level correlates with survival in advanced gastrointestinal cancer patients but is not an independent prognostic indicator

1 reference

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21 January 2018

Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer

1 reference

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21 January 2018

NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon?

1 reference

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21 January 2018

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

1 reference

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21 January 2018

B-cell-derived lymphotoxin promotes castration-resistant prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Aberrant activation of the androgen receptor by NF-kappaB2/p52 in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

NFκB signalling is upregulated in a subset of castrate-resistant prostate cancer patients and correlates with disease progression

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Interleukin-8 signaling attenuates TRAIL- and chemotherapy-induced apoptosis through transcriptional regulation of c-FLIP in prostate cancer cells

1 reference

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21 January 2018

Potentiation of inflammatory CXCL8 signalling sustains cell survival in PTEN-deficient prostate carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Infiltrating macrophages promote prostate tumorigenesis via modulating androgen receptor-mediated CCL4-STAT3 signaling.

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Transcription factor Stat5 knockdown enhances androgen receptor degradation and delays castration-resistant prostate cancer progression in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Relative copy number gain of MYC in diagnostic needle biopsies is an independent prognostic factor for prostate cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

An immunohistochemical signature comprising PTEN, MYC, and Ki67 predicts progression in prostate cancer patients receiving adjuvant docetaxel after prostatectomy

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Transcriptional amplification in tumor cells with elevated c-Myc.

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Aberrations of EZH2 in cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

The role of murine models of prostate cancer in drug target discovery and validation

1 reference

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21 January 2018

The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression

1 reference

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21 January 2018

Medroxyprogesterone acetate downregulates cytokine gene expression in mouse fibroblast cells.

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21 January 2018

Activation of toll-like receptor 2 in acne triggers inflammatory cytokine responses

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21 January 2018

Titanium particles induce the immediate early stress responsive chemokines IL-8 and MCP-1 in osteoblasts

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Bipolar androgen therapy: the rationale for rapid cycling of supraphysiologic androgen/ablation in men with castration resistant prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Separating the drivers from the driven: Integrative network and pathway approaches aid identification of disease biomarkers from high-throughput data

1 reference

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21 January 2018

Integrating molecular and network biology to decode endocytosis

1 reference

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21 January 2018

Single-tube linear DNA amplification (LinDA) for robust ChIP-seq.

1 reference

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21 January 2018

A carrier-assisted ChIP-seq method for estrogen receptor-chromatin interactions from breast cancer core needle biopsy samples.

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor

1 reference

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21 January 2018

Mechanisms of resistance to small molecule kinase inhibition in the treatment of solid tumors

1 reference

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21 January 2018

Whole-exome sequencing reveals recurrent somatic mutation networks in cancer.

1 reference

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21 January 2018

Potential pitfalls in microRNA profiling

1 reference

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21 January 2018

Progress in concurrent analysis of loss of heterozygosity and comparative genomic hybridization utilizing high density single nucleotide polymorphism arrays

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Array comparative genomic hybridization copy number profiling: a new tool for translational research in solid malignancies

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Amplitude modulation of androgen signaling by c-MYC.

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulation

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Androgen receptor-independent function of FoxA1 in prostate cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Cross-regulation between FOXA1 and ErbB2 signaling in estrogen receptor-negative breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

A functionally significant cross-talk between androgen receptor and ErbB2 pathways in estrogen receptor negative breast cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

NF-kappaB regulates androgen receptor expression and prostate cancer growth

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: an immunohistochemical study

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

21 January 2018

EFFECT OF ORCHIECTOMY AND IRRADIATION ON CANCER OF THE PROSTATE

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Recurrent gene fusions in prostate cancer: their clinical implications and uses

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Role of the TMPRSS2-ERG gene fusion in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

The FoxA factors in organogenesis and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Androgen regulation of the TMPRSS2 gene and the effect of a SNP in an androgen response element

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Transcription factor Stat5 synergizes with androgen receptor in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Clinical and pathologic significance of activation of signal transducer and activator of transcription 3 in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

SRC-3 is required for prostate cancer cell proliferation and survival

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Bioinformatics approach leads to the discovery of the TMPRSS2:ETS gene fusion in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC3678

31 March 2020

Targeting transcription factor Stat5a/b as a therapeutic strategy for prostate cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24561445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interrogating genomic and epigenomic data to understand prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24561445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ChIP-exo method for identifying genomic location of DNA-binding proteins with near-single-nucleotide accuracy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24561445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NRC3678

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

ResearchGate publication ID

0 references

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