Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy (Q37572139)

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scientific article published on 22 October 2013

Language	Label	Description	Also known as
English	Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy	scientific article published on 22 October 2013

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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7

object named as

Diane M Robins

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Europe PubMed Central

PMC publication ID

21 August 2017

object named as

Hiroaki Adachi

4

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6

object named as

Gen Sobue

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Europe PubMed Central

21 August 2017

PMC publication ID

author name string

Jason P Chua

1

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Europe PubMed Central

PMC publication ID

21 August 2017

Satya L Reddy

2

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Europe PubMed Central

PMC publication ID

21 August 2017

Diane E Merry

3

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Europe PubMed Central

PMC publication ID

21 August 2017

Masahisa Katsuno

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Andrew P Lieberman

8

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Europe PubMed Central

PMC publication ID

21 August 2017

publication date

22 October 2013

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Europe PubMed Central

PMC publication ID

21 August 2017

Human Molecular Genetics

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Europe PubMed Central

PMC publication ID

21 August 2017

23

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Europe PubMed Central

PMC publication ID

21 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

1376-1386

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Europe PubMed Central

PMC publication ID

21 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3919011/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

ZKSCAN3 is a master transcriptional repressor of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Cellular and molecular mechanisms of muscle atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Guidelines for the use and interpretation of assays for monitoring autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Insulinlike growth factor (IGF)-1 administration ameliorates disease manifestations in a mouse model of spinal and bulbar muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

TFEB links autophagy to lysosomal biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Proteasomal and autophagic degradative activities in spinal and bulbar muscular atrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Methods in mammalian autophagy research

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Tor directly controls the Atg1 kinase complex to regulate autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Autophagy in neurite injury and neurodegeneration: in vitro and in vivo models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease

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23 August 2017

Therapeutic exercise for people with amyotrophic lateral sclerosis or motor neuron disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Autophagy fights disease through cellular self-digestion

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

FoxO3 controls autophagy in skeletal muscle in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model

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23 August 2017

Abnormalities of germ cell maturation and sertoli cell cytoskeleton in androgen receptor 113 CAG knock-in mice reveal toxic effects of the mutant protein

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23 August 2017

Development by self-digestion: molecular mechanisms and biological functions of autophagy

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23 August 2017

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

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23 August 2017

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Identification of ubiquitin ligases required for skeletal muscle atrophy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919011

23 August 2017

Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation

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23 August 2017

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

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23 August 2017

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

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23 August 2017

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

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23 August 2017

Control of autophagy as a therapy for neurodegenerative disease

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6 September 2017

Regulation of TFEB and V-ATPases by mTORC1.

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6 September 2017

The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor

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6 September 2017

Quantitation of "autophagic flux" in mature skeletal muscle

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14 September 2017

Induction of macroautophagy by exogenously introduced calcium

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14 September 2017

Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity

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14 September 2017

Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells

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Rapamycin-induced autophagy aggravates pathology and weakness in a mouse model of VCP-associated myopathy

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28 September 2017

A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1.

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25 June 2018

p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model.

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1 September 2018

Muscle atrophy in Limb Girdle Muscular Dystrophy 2A: a morphometric and molecular study

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1 September 2018

Effect of aerobic training in patients with spinal and bulbar muscular atrophy (Kennedy disease).

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Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size

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1 September 2018

Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle

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1 September 2018

Transglutaminase potentiates ligand-dependent proteasome dysfunction induced by polyglutamine-expanded androgen receptor

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1 September 2018

Ligand promotes intranuclear inclusions in a novel cell model of spinal and bulbar muscular atrophy

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1 September 2018

Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.

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Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

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Altered transcriptional regulation in cells expressing the expanded polyglutamine androgen receptor

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TFEB regulates autophagy: An integrated coordination of cellular degradation and recycling processes

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Akt blocks ligand binding and protects against expanded polyglutamine androgen receptor toxicity

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12 December 2020

based on heuristic

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Skeletal Muscle Is a Primary Target of SOD1G93A-Mediated Toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24150846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subclinical phenotypic expressions in heterozygous females of X-linked recessive bulbospinal neuronopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24150846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced transcriptional regulatory competence of the androgen receptor in X-linked spinal and bulbar muscular atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24150846

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDT527

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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