Cytokine-mediated β-cell damage in PARP-1-deficient islets. (Q36200224)

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Language	Label	Description	Also known as
English	Cytokine-mediated β-cell damage in PARP-1-deficient islets.	scientific article

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30 January 2020

Cytokine-mediated β-cell damage in PARP-1-deficient islets (English)

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30 January 2020

Gordon P Meares

2

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30 January 2020

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Teresa Andreone

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30 January 2020

Katherine J Hughes

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30 January 2020

Polly A Hansen

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30 January 2020

John A Corbett

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30 January 2020

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24 April 2012

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30 January 2020

American Journal of Physiology - Endocrinology and Metabolism

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30 January 2020

303

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30 January 2020

2

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30 January 2020

E172-9

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30 January 2020

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IRE1-dependent activation of AMPK in response to nitric oxide

1 reference

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FoxO1 and SIRT1 regulate beta-cell responses to nitric oxide

1 reference

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1 October 2017

Poly(ADP-ribose) polymerase-1 (PARP-1) and its therapeutic implications

1 reference

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1 reference

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1 reference

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1 October 2017

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1 reference

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1 October 2017

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1 reference

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Poly ADP-ribose polymerase-1: an international molecule of mystery

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The mechanisms of alloxan- and streptozotocin-induced diabetes

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1 October 2017

Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus

1 reference

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1 October 2017

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1 reference

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1 October 2017

Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines

1 reference

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Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1

1 reference

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1 October 2017

Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity

1 reference

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1 October 2017

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

1 reference

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1 October 2017

Poly(ADP-ribose) polymerases: homology, structural domains and functions. Novel therapeutical applications.

1 reference

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1 October 2017

Alkylating DNA damage stimulates a regulated form of necrotic cell death

1 reference

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1 October 2017

Apoptotic signal transduction pathways in diabetes

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1 October 2017

Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

1 October 2017

Poly(ADP-ribose) polymerase-1 regulates activation of activator protein-1 in murine fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

1 October 2017

Recent advances in the Okamoto model: the CD38-cyclic ADP-ribose signal system and the regenerating gene protein (Reg)-Reg receptor system in beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

1 October 2017

Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis

1 reference

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1 October 2017

Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes

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1 October 2017

Potential role of PKR in double-stranded RNA-induced macrophage activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

1 October 2017

Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

1 October 2017

Discovering new ADP-ribose polymer cycles: protecting the genome and more

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

1 October 2017

Nitric oxide-induced damage to mtDNA and its subsequent repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

1 October 2017

The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

1 October 2017

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

1 reference

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1 October 2017

PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

1 October 2017

pADPRT-2: a novel mammalian polymerizing(ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegans

1 reference

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1 October 2017

A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologues

1 reference

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1 October 2017

Poly(ADP-ribose) polymerase in the cellular response to DNA damage, apoptosis, and disease

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1 October 2017

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

1 October 2017

Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

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Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

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1 October 2017

Double-stranded RNA-induced inducible nitric-oxide synthase expression and interleukin-1 release by murine macrophages requires NF-kappaB activation

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1 October 2017

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Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1.

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1 October 2017

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1 reference

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1 reference

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Potent beta-cell protection in vitro by an isoquinolinone-derived PARP inhibitor.

1 reference

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2 July 2018

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1 reference

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2 July 2018

Toxicity determined in vitro by morphological alterations and neutral red absorption

1 reference

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2 July 2018

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1 reference

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22 September 2018

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22 September 2018

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1 reference

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22 September 2018

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1 reference

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22 September 2018

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1 reference

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22 September 2018

Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00055.2012

21 January 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22535743

12 December 2020

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inferred from PubMed ID database lookup

DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22535743

12 December 2020

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22535743

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inferred from PubMed ID database lookup

Isolation of islets of Langerhans from rodent pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22535743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of chemically generated nitric oxide towards pancreatic islet cells can be prevented by nicotinamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22535743

12 December 2020

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inferred from PubMed ID database lookup

Islet cell DNA is a target of inflammatory attack by nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22535743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical evidence for nitric oxide formation from streptozotocin in isolated pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22535743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide prevents interleukin-1 effects on accumulated insulin release and nitric oxide production in rat islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22535743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/22535743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of ADP-ribosylation impair inducible nitric oxide synthase gene transcription through inhibition of NF kappa B activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22535743

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Newly discovered anti-inflammatory properties of the benzamides and nicotinamides

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inferred from PubMed ID database lookup

Identifiers

10.1152/AJPENDO.00055.2012

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30 January 2020

PMC publication ID

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Europe PubMed Central

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30 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

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