Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters (Q35927759)

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scientific article published on 24 August 2012

Language	Label	Description	Also known as
English	Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters	scientific article published on 24 August 2012

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Minhao Wu

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Bin Dong

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Aiqin Cao

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Hai Li

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Jingwen Liu

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

publication date

24 August 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Atherosclerosis

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

224

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

401-410

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528917

2 October 2017

The novel function of HINFP as a co-activator in sterol-regulated transcription of PCSK9 in HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528917

2 October 2017

Effects of currently prescribed LDL-C-lowering drugs on PCSK9 and implications for the next generation of LDL-C-lowering agents

1 reference

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2 October 2017

Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9

1 reference

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2 October 2017

Janus kinase activation by cytokine oncostatin M decreases PCSK9 expression in liver cells

1 reference

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2 October 2017

Suppression of Idol expression is an additional mechanism underlying statin-induced up-regulation of hepatic LDL receptor expression

1 reference

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2 October 2017

Fasting reduces plasma proprotein convertase, subtilisin/kexin type 9 and cholesterol biosynthesis in humans

1 reference

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High-dose atorvastatin causes a rapid sustained increase in human serum PCSK9 and disrupts its correlation with LDL cholesterol

1 reference

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Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters

1 reference

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2 October 2017

Statins and ezetimibe modulate plasma proprotein convertase subtilisin kexin-9 (PCSK9) levels

1 reference

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2 October 2017

Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine

1 reference

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2 October 2017

Inhibition of PCSK9: a powerful weapon for achieving ideal LDL cholesterol levels

1 reference

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2 October 2017

A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates

1 reference

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2 October 2017

Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells

1 reference

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2 October 2017

Importance of proprotein convertase subtilisin/kexin type 9 in the hormonal and dietary regulation of rat liver low-density lipoprotein receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528917

2 October 2017

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

1 reference

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2 October 2017

Plasma PCSK9 levels are significantly modified by statins and fibrates in humans

1 reference

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2 October 2017

Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528917

2 October 2017

Berberine decreases PCSK9 expression in HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528917

2 October 2017

Plasma PCSK9 preferentially reduces liver LDL receptors in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528917

2 October 2017

Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528917

2 October 2017

Sterol-dependent regulation of proprotein convertase subtilisin/kexin type 9 expression by sterol-regulatory element binding protein-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528917

2 October 2017

Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4528917

2 October 2017

Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice

1 reference

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2 October 2017

Genetics of apolipoprotein B and apolipoprotein AI and premature coronary artery disease

1 reference

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2 October 2017

Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c

1 reference

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The LDL receptor: how acid pulls the trigger

1 reference

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2 October 2017

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

1 reference

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2 October 2017

Predictors of atherosclerosis

1 reference

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2 October 2017

Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia

1 reference

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Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

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Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice

1 reference

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Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

1 reference

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Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

1 reference

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1 reference

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Low-density lipoprotein receptors in rat adipocytes: regulation with fasting.

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1 reference

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Circulating proprotein convertase subtilisin kexin type 9 has a diurnal rhythm synchronous with cholesterol synthesis and is reduced by fasting in humans

1 reference

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Fasting induces hyperlipidemia in mice overexpressing proprotein convertase subtilisin kexin type 9: lack of modulation of very-low-density lipoprotein hepatic output by the low-density lipoprotein receptor.

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12 December 2020

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10.1016/J.ATHEROSCLEROSIS.2012.08.012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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