Sensors of the innate immune system: their link to rheumatic diseases (Q35623130)

9 August 2017

1 reference

title

Sensors of the innate immune system: their link to rheumatic diseases (English)

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9 August 2017

Bruce Beutler

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9 August 2017

Rosana Gonzalez-Quintial

object named as

Rosana Gonzalez-Quintial

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9 August 2017

author name string

Argyrios N Theofilopoulos

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9 August 2017

Brian R Lawson

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9 August 2017

Yi T Koh

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9 August 2017

Michael E Stern

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9 August 2017

Dwight H Kono

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9 August 2017

Roberto Baccala

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9 August 2017

language of work or name

English

0 references

publication date

9 February 2010

1 reference

Nature Reviews Rheumatology

9 August 2017

published in

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

146-156

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Sensors of the innate immune system: their mode of action

9 August 2017

cites work

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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A Tlr7 translocation accelerates systemic autoimmunity in murine lupus

27 July 2018

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Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

27 July 2018

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Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS)

27 July 2018

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27 July 2018

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Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome

27 July 2018

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Gout-associated uric acid crystals activate the NALP3 inflammasome

27 July 2018

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Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL.

27 July 2018

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TLR ignores methylated RNA?

27 July 2018

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Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

27 July 2018

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27 July 2018

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Interferons as pathogenic effectors in autoimmunity

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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CARD15 mutations in Blau syndrome

27 July 2018

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27 July 2018

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27 July 2018

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The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments

27 July 2018

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

27 July 2018

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Features of systemic lupus erythematosus in Dnase1-deficient mice

27 July 2018

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Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease.

27 July 2018

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Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

25 September 2018

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25 September 2018

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TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus

25 September 2018

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Homozygosity for DNASE2 single nucleotide polymorphisms in the 5'-regulatory region is associated with rheumatoid arthritis.

25 September 2018

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Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

25 September 2018

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Trex1 prevents cell-intrinsic initiation of autoimmunity

25 September 2018

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Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.

25 September 2018

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Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

25 September 2018

1 reference

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An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity

25 September 2018

1 reference

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The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Differential MHC class II presentation of a pathogenic autoantigen during health and disease

25 September 2018

1 reference

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Accelerated macrophage apoptosis induces autoantibody formation and organ damage in systemic lupus erythematosus

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Systemic exposure to irradiated apoptotic cells induces autoantibody production

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437225

Activation of natural interferon-alpha producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines

25 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Lupus-like disease and high interferon levels corresponding to trisomy of the type I interferon cluster on chromosome 9p

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Viral 5'-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Immunoregulation of SLE-like disease by the IL-1 receptor: disease modifying activity on BDF1 hybrid mice and MRL autoimmune mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Type I interferons might form the link between Toll-like receptor (TLR) 3/7 and TLR4-mediated synovial inflammation in rheumatoid arthritis (RA)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 88

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Activation of the type I interferon system in primary Sjögren's syndrome: a possible etiopathogenic mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

A possible mechanism for endogenous activation of the type I interferon system in myositis patients with anti-Jo-1 or anti-Ro 52/anti-Ro 60 autoantibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Anakinra for flares of pyogenic arthritis in PAPA syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2009.278

Murine models of systemic lupus erythematosus

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20142813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRRHEUM.2009.278

1 reference

9 August 2017

1 reference

9 August 2017

1 reference