The pain of antisense: in vivo application of antisense oligonucleotides for functional genomics in pain and analgesia. (Q35205482)

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English	The pain of antisense: in vivo application of antisense oligonucleotides for functional genomics in pain and analgesia.	scientific article

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7 November 2019

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The pain of antisense: in vivo application of antisense oligonucleotides for functional genomics in pain and analgesia (English)

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7 November 2019

functional genomics

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Lucy Vulchanova

2

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7 November 2019

author name string

Laura S Stone

1

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7 November 2019

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1 August 2003

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7 November 2019

Advanced Drug Delivery Reviews

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7 November 2019

55

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7 November 2019

8

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7 November 2019

1081-1112

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7 November 2019

Cell damage excites nociceptors through release of cytosolic ATP.

1 reference

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7 January 2021

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P2X receptors in peripheral neurons

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https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

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Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons

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https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

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Painful connection for ATP.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

A P2X purinoceptor expressed by a subset of sensory neurons

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https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct ATP receptors on pain-sensing and stretch-sensing neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

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P2X3 is expressed by DRG neurons that terminate in inner lamina II

1 reference

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7 January 2021

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The expression of P2X3 purinoreceptors in sensory neurons: effects of axotomy and glial-derived neurotrophic factor.

1 reference

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7 January 2021

based on heuristic

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Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

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Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

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Functional downregulation of P2X3 receptor subunit in rat sensory neurons reveals a significant role in chronic neuropathic and inflammatory pain.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

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Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

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Na+ channel immunolocalization in peripheral mammalian axons and changes following nerve injury and neuroma formation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

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Ion channels of nociception.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Distribution of the tetrodotoxin-resistant sodium channel PN3 in rat sensory neurons in normal and neuropathic conditions.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Redistribution of Na(V)1.8 in uninjured axons enables neuropathic pain.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

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Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

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A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

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The involvement of the tetrodotoxin-resistant sodium channel Na(v)1.8 (PN3/SNS) in a rat model of visceral pain.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

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Antinociceptive effects after intrathecal administration of phosphodiester-, 2'-O-allyl-, and C-5-propyne-modified antisense oligodeoxynucleotides targeting the NMDAR1 subunit in mouse

1 reference

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7 January 2021

based on heuristic

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Antisense oligonucleotides to N-methyl-D-aspartate receptor subunits attenuate formalin-induced nociception in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of potassium channels in the antinociception induced by agonists of alpha2-adrenoceptors

1 reference

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7 January 2021

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The role of potassium channels in antihistamine analgesia.

1 reference

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7 January 2021

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Differential knockdown of delta-opioid receptor subtypes in the rat brain by antisense oligodeoxynucleotides targeting mRNA.

1 reference

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7 January 2021

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Selective inhibition of [D-Ala2, Glu4]deltorphin antinociception by supraspinal, but not spinal, administration of an antisense oligodeoxynucleotide to an opioid delta receptor

1 reference

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7 January 2021

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An antisense oligodeoxynucleotide to the delta opioid receptor (DOR-1) inhibits morphine tolerance and acute dependence in mice

1 reference

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7 January 2021

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inferred from DOI database lookup

Antisense oligodeoxynucleotide to a delta-opioid receptor blocks the antinociception induced by cold water swimming

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense oligodeoxynucleotide to delta opioid receptors attenuates morphine dependence in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

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inferred from DOI database lookup

kappa -opioid receptor agonists modulate visceral nociception at a novel, peripheral site of action

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

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Antisense mapping the MOR‐1 opioid receptor: evidence for alternative splicing and a novel morphine‐6β‐glucuronide receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

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Identification and characterization of three new alternatively spliced mu-opioid receptor isoforms.

1 reference

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7 January 2021

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Antisense oligodeoxynucleotide targeting distinct exons of the cloned mu-opioid receptor distinguish between endomorphin-1 and morphine supraspinal antinociception in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

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Spinal pretreatment with antisense oligodeoxynucleotides against exon-1, -4, or -8 of mu-opioid receptor clone leads to differential loss of spinal endomorphin-1-and endomorphin-2-induced antinociception in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

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Anatomical and functional correlation of the endomorphins with mu opioid receptor splice variants

1 reference

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7 January 2021

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Pharmacological characterization of morphine-6-sulfate and codeine-6-sulfate

1 reference

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7 January 2021

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Effect of antisense knock-down of alpha(2a)- and alpha(2c)-adrenoceptors on the antinociceptive action of clonidine on trigeminal nociception in the rat.

1 reference

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7 January 2021

based on heuristic

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The α2aAdrenergic Receptor Subtype Mediates Spinal Analgesia Evoked by α2Agonists and Is Necessary for Spinal Adrenergic–Opioid Synergy

1 reference

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7 January 2021

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1 reference

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alpha(2C)-Adrenergic receptors mediate spinal analgesia and adrenergic-opioid synergy

1 reference

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7 January 2021

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1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Knockdown of spinal metabotropic glutamate receptor 1 (mGluR(1)) alleviates pain and restores opioid efficacy after nerve injury in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense oligonucleotide knockdown of mGluR1 alleviates hyperalgesia and allodynia associated with chronic inflammation

1 reference

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7 January 2021

based on heuristic

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Attenuation of morphine tolerance after antisense oligonucleotide knock-down of spinal mGluR1.

1 reference

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1 reference

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7 January 2021

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Intrathecal administration of PNA targeting galanin receptor reduces galanin-mediated inhibitory effect in the rat spinal cord

1 reference

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7 January 2021

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Antisense oligodeoxynucleotide to the CCKB receptor produces naltrindole- and [Leu5]enkephalin antiserum-sensitive enhancement of morphine antinociception

1 reference

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7 January 2021

based on heuristic

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Loss of muscarinic antinociception by antisense inhibition of M(1) receptors

1 reference

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7 January 2021

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Antisense 'knockdowns' of M1 receptors induces transient anterograde amnesia in mice

1 reference

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7 January 2021

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Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Intraperitoneal injection of antisense peptide nucleic acids targeted to the mu receptor decreases response to morphine and receptor protein levels in rat brain

1 reference

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7 January 2021

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inferred from DOI database lookup

Specific gene blockade shows that peptide nucleic acids readily enter neuronal cells in vivo

1 reference

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7 January 2021

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Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression

1 reference

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7 January 2021

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inferred from DOI database lookup

'Knock-down' of spinal CB1 receptors produces abnormal pain and elevates spinal dynorphin content in mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense oligodeoxynucleotide treatment to the brain cannabinoid receptor inhibits antinociception.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential effects of antisense oligodeoxynucleotides directed against g(zalpha) and g(oalpha) on antinociception produced by spinal opioid and alpha(2) adrenergic receptor agonists

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

G Proteins and Opioid Receptor-Mediated Signalling

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo modulation of G proteins and opioid receptor function by antisense oligodeoxynucleotides.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of the G protein gamma(2) subunit in opioid antinociception in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Knockdown of spinal opioid receptors by antisense targeting beta-arrestin reduces morphine tolerance and allodynia in rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: Evidence for opposing NO actions on morphine analgesia and tolerance

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotrophin-3 antisense oligonucleotide attenuates nerve injury-induced Abeta-fibre sprouting

1 reference

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7 January 2021

based on heuristic

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Inhibition of carrageenan-induced spinal c-Fos activation by systemically administered c-fos antisense oligodeoxynucleotides may be facilitated by local opening of the blood-spinal cord barrier

1 reference

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7 January 2021

based on heuristic

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Properties of cloned and expressed human RNase H1.

1 reference

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7 January 2021

based on heuristic

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The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Modification of phosphorothioate oligonucleotides yields potent analogs with minimal toxicity for antisense experiments in the CNS.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Fully modified 2' MOE oligonucleotides redirect polyadenylation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-alpha chain

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

RNA interference in adult mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Virally mediated delivery of enkephalin and other neuropeptide transgenes in experimental pain models

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of RNA secondary structure on cellular antisense activity

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The experimental use of antisense oligonucleotides: a guide for the perplexed

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

A good antisense molecule is hard to find

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Selection of effective antisense oligodeoxynucleotides with a green fluorescent protein-based assay

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Tetranucleotide GGGA motif in primary RNA transcripts. Novel target site for antisense design

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase I trial of ISIS 104838, a 2'-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

RNA accessibility prediction: a theoretical approach is consistent with experimental studies in cell extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Theoretical and experimental approaches to design effective antisense oligonucleotides.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Concepts to automate the theoretical design of effective antisense oligonucleotides

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

RNA mapping: selection of potent oligonucleotide sequences for antisense experiments

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mapping of RNA accessible sites for antisense experiments with oligonucleotide libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

A selection system for identifying accessible sites in target RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Selecting effective antisense reagents on combinatorial oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of sequence motifs in oligonucleotides whose presence is correlated with antisense activity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Artificial neural network prediction of antisense oligodeoxynucleotide activity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

ODNBase--a web database for antisense oligonucleotide effectiveness studies. Oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

CpG motifs in bacterial DNA trigger direct B-cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence-specific interaction of alpha-beta-anomeric double-stranded DNA with the p50 subunit of NF kappa B: application to the decoy approach

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Specificity of antisense oligonucleotides in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Peripheral nerve injury alters the alpha2 adrenoceptor subtype activated by clonidine for analgesia

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense technology reveals the alpha2A adrenoceptor to be the subtype mediating the hypnotic response to the highly selective agonist, dexmedetomidine, in the locus coeruleus of the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense suppression of GABA(A) receptor beta subunit levels in cultured cerebellar granule neurons demonstrates their importance in receptor expression

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of the gene expression of N-methyl-D-aspartate receptor NR2B subunit in the rat neostriatum by a single dose of specific antisense oligodeoxynucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Complementary profiling of gene expression at the transcriptome and proteome levels in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic interrogation of mechanism(s) underlying cellular responses to toxicants

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense DNAs as multisite genomic modulators identified by DNA microarray

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential effects of intrastriatally infused fully and endcap phosphorothioate antisense oligonucleotides on morphology, histochemistry and prodynorphin expression in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Centrally administered oligodeoxynucleotides in rats: occurrence of non-specific effects

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Potent and nontoxic antisense oligonucleotides containing locked nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense properties of peptide nucleic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Design of antisense oligonucleotides stabilized by locked nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

A short phosphodiester window is sufficient to direct RNase H-dependent RNA cleavage by antisense peptide nucleic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Formation of a G-tetrad and higher order structures correlates with biological activity of the RelA (NF-kappaB p65) 'antisense' oligodeoxynucleotide.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific inhibition of the rat ligand-gated ion channel P2X3 function via methoxyethoxy-modified phosphorothioated antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense oligonucleotide blockade of tumor necrosis factor-alpha in two murine models of colitis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The spread and uptake pattern of intracerebrally administered oligonucleotides in nerve and glial cell populations of the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Intrastriatal and intraventricular injections of oligodeoxynucleotides in the rat brain: tissue penetration, intracellular distribution and c-fos antisense effects

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular uptake of intracerebroventricularly administered biotin- or digoxigenin-labeled antisense oligodeoxynucleotides in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense imaging of gene expression in the brain in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Drug delivery of antisense molecules to the brain for treatment of Alzheimer's disease and cerebral AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Transdermal use of phosphorodiamidate morpholino oligomer AVI-4472 inhibits cytochrome P450 3A2 activity in male rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic catheterization of the spinal subarachnoid space

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Intrathecal morphine in mice: a new technique

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic intrathecal infusions after spinal cord injury cause scarring and compression

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Lumbar catheterization of the spinal subarachnoid space in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Covalent Protein−Oligonucleotide Conjugates for Efficient Delivery of Antisense Molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Peptide-oligonucleotide phosphorothioate conjugates with membrane translocation and nuclear localization properties.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Elevated messenger RNA levels after antisense oligodeoxynucleotide treatment in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of spinal protein kinase Calpha expression by an antisense oligonucleotide attenuates morphine infusion-induced tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective blockade of peripheral delta opioid agonist induced antinociception by intrathecal administration of delta receptor antisense oligodeoxynucleotide.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotides to a delta opioid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The presence and role of the tetrodotoxin-resistant sodium channel Na(v)1.9 (NaN) in nociceptive primary afferent neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative real-time RT-PCR using hybridization probes and imported standard curves for cytokine gene expression analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Peptide nucleic acid antisense prolongs skin allograft survival by means of blockade of CXCR3 expression directing T cells into graft.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Advances in proteome analysis by mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Advances in proteome analysis by mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct analysis of protein complexes using mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The application of mass spectrometry to membrane proteomics

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2803%2900105-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0169-409X(03)00105-4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12935946%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12935946%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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