Conditional mouse models of sporadic cancer (Q34632032)

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Language	Label	Description	Also known as
English	Conditional mouse models of sporadic cancer	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

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Europe PubMed Central

Conditional mouse models of sporadic cancer (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

1

object named as

Jos Jonkers

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Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Anton Berns

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Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

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publication date

1 April 2002

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Europe PubMed Central

PubMed publication ID

3 August 2017

Nature Reviews Cancer

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Europe PubMed Central

PubMed publication ID

3 August 2017

2

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Europe PubMed Central

PubMed publication ID

3 August 2017

4

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Europe PubMed Central

PubMed publication ID

3 August 2017

251-265

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Europe PubMed Central

PubMed publication ID

3 August 2017

SOME POSSIBLE EFFECTS OF NURSING ON THE MAMMARY GLAND TUMOR INCIDENCE IN MICE.

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Animal models of tumor-suppressor genes.

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Conditional control of gene expression in the mouse

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Inducible gene targeting in mice using the Cre/lox system

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Turning on tumors to study cancer progression

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Development of a flexible and specific gene delivery system for production of murine tumor models

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Angiogenesis in cancer and other diseases

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Building 'validated' mouse models of human cancer

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

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https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

A system for tissue-specific gene targeting: transgenic mice susceptible to subgroup A avian leukosis virus-based retroviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Gliomagenesis: genetic alterations and mouse models

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Induction of ovarian cancer by defined multiple genetic changes in a mouse model system

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Essential role for oncogenic Ras in tumour maintenance

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Reversible tumorigenesis by MYC in hematopoietic lineages

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Sensitivity to myc-induced apoptosis is retained in spontaneous and transplanted lymphomas of CD2-mycER mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Reversibility of acute B-cell leukaemia induced by BCR-ABL1.

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Conditional expression of fibroblast growth factor-7 in the developing and mature lung.

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Generalized lacZ expression with the ROSA26 Cre reporter strain

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus.

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Mammalian genomes contain active recombinase recognition sites

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase.

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Rapid Colorectal Adenoma Formation Initiated by Conditional Targeting of the Apc Gene

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Tissue microarrays for high-throughput molecular profiling of tumor specimens

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Multicolour spectral karyotyping of mouse chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Expression profiling and identification of novel genes in hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

The Celera Discovery System.

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

The Ensembl genome database project

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Acquired, nonrandom chromosomal abnormalities associated with the development of acute promyelocytic leukemia in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Specific protection against breast cancers by cyclin D1 ablation

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Scaling down imaging: molecular mapping of cancer in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Role of gene knockout mice in understanding the mechanisms of chemical toxicity and carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Regulated transposition of a fish transposon in the mouse germ line

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Complementation tagging of cooperating oncogenes in knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Carcinogenesis in mouse and human cells: parallels and paradoxes

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Brca1 required for T cell lineage development but not TCR loci rearrangement.

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Ligand-activated site-specific recombination in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Cre-mediated somatic site-specific recombination in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Genetic determinants of response to chemotherapy in transgenic mouse mammary and salivary tumors

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Genetic analysis of chemoresistance in primary murine lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Combinatorial chemoprevention of intestinal neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

A Farnesyltransferase Inhibitor Induces Tumor Regression in Transgenic Mice Harboring Multiple Oncogenic Mutations by Mediating Alterations in Both Cell Cycle Control and Apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

A farnesyl transferase inhibitor suppresses TPA-mediated skin tumor development without altering hyperplasia in the ras transgenic Tg.AC mouse

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Treatment of Bcr/Abl-positive acute lymphoblastic leukemia in P190 transgenic mice with the farnesyl transferase inhibitor SCH66336.

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FNRC777

31 March 2020

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1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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