Engineering of Glarea lozoyensis for exclusive production of the pneumocandin B0 precursor of the antifungal drug caspofungin acetate (Q34454935)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25527531%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

title

Engineering of Glarea lozoyensis for exclusive production of the pneumocandin B0 precursor of the antifungal drug caspofungin acetate (English)

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25 February 2020

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ChEBI release 2020-05-28

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25 February 2020

Li Chen

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25 February 2020

Qun Yue

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25 February 2020

Yan Li

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25 February 2020

Xuemei Niu

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25 February 2020

Meichun Xiang

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25 February 2020

Wenzhao Wang

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25 February 2020

Xingzhong Liu

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25 February 2020

Zhiqiang An

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25 February 2020

language of work or name

English

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publication date

19 December 2014

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full work available at URL

25 February 2020

https://aem.asm.org/content/aem/81/5/1550.full.pdf

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19 March 2024

https://api.unpaywall.org/v2/10.1128/aem.03256-14?email=unpaywall_01@example.com

published in

Applied and Environmental Microbiology

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25 February 2020

volume

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25 February 2020

issue

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25 February 2020

page(s)

1550-1558

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25 February 2020

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19 March 2024

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access restriction status

open access

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inferred from online access status

cites work

New insights into the echinocandins and other fungal non-ribosomal peptides and peptaibiotics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Discovery and development of first in class antifungal caspofungin (CANCIDAS®)--a case study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in the fungus Glarea lozoyensis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Echinocandins: production and applications

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

EcdGHK are three tailoring iron oxygenases for amino acid building blocks of the echinocandin scaffold

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Identification and characterization of the echinocandin B biosynthetic gene cluster from Emericella rugulosa NRRL 11440.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Genome Sequence of the Fungus Glarea lozoyensis: the First Genome Sequence of a Species from the Helotiaceae Family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

M-Coffee: combining multiple sequence alignment methods with T-Coffee

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Echinocandin antifungal drugs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Caspofungin: the first in a new class of antifungal agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

L-671,329, a new antifungal agent. I. Fermentation and isolation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Pneumocandins from Zalerion arboricola. V. Glutamic acid- and leucine-derived amino acids in pneumocandin A0 (L-671,329) and distinct origins of the substituted proline residues in pneumocandins A0 and B0

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Pneumocandin biosynthesis: involvement of a trans-selective proline hydroxylase.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Efficient disruption of a polyketide synthase gene ( pks1) required for melanin synthesis through Agrobacterium-mediated transformation of Glarea lozoyensis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Biosynthesis of 4-methylproline in cyanobacteria: cloning of nosE and nosF genes and biochemical characterization of the encoded dehydrogenase and reductase activities

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Effects of amino acid and trace element supplementation on pneumocandin production by Glarea lozoyensis: impact on titer, analogue levels, and the identification of new analogues of pneumocandin B(0).

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325176

Pneumocandins from Zalerion arboricola. I. Discovery and isolation

27 October 2018

1 reference

12 December 2020

Pneumocandins from Zalerion arboricola. II. Modification of product spectrum by mutation and medium manipulation

1 reference

12 December 2020

Pneumocandins from Zalerion arboricola. IV. Biological evaluation of natural and semisynthetic pneumocandins for activity against Pneumocystis carinii and Candida species

1 reference

12 December 2020

Improvement in the titer of echinocandin-type antibiotics: a magnesium-limited medium supporting the biphasic production of pneumocandins A0 and B0

1 reference

12 December 2020

Identifiers

DOI

10.1128/AEM.03256-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25527531%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

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25 February 2020

PubMed publication ID

25527531

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25527531%20AND%20SRC:MED&resulttype=core&format=json