Development of a multi-step leukemogenesis model of MLL-rearranged leukemia using humanized mice (Q34321077)

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Language	Label	Description	Also known as
English	Development of a multi-step leukemogenesis model of MLL-rearranged leukemia using humanized mice	scientific article

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22745659%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Development of a multi-step leukemogenesis model of MLL-rearranged leukemia using humanized mice (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22745659%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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13

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6 February 2020

author name string

Kunihiko Moriya

1

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6 February 2020

Makiko Suzuki

2

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6 February 2020

Yohei Watanabe

3

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6 February 2020

Takeshi Takahashi

4

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6 February 2020

Yoko Aoki

5

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6 February 2020

Toru Uchiyama

6

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6 February 2020

Satoru Kumaki

7

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6 February 2020

Yoji Sasahara

8

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6 February 2020

Masayoshi Minegishi

9

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6 February 2020

Shigeo Kure

10

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6 February 2020

Shigeru Tsuchiya

11

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6 February 2020

Kazuo Sugamura

12

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6 February 2020

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20 June 2012

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6 February 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22745659%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22745659%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

6

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6 February 2020

e37892

1 reference

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6 February 2020

copyright license

Creative Commons Attribution 4.0 International

20 June 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

The heterogeneity of pediatric MLL-rearranged acute myeloid leukemia

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BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells

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Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.

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6 July 2018

MLL fusions: pathways to leukemia

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6 July 2018

MLL/AF10(OM-LZ)-immortalized cells expressed cytokines and induced host cell proliferation in a mouse bone marrow transplantation model

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6 July 2018

Therapeutic targeting of MLL.

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Molecular bases of myelodysplastic syndromes: lessons from animal models

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Efficient tumour formation by single human melanoma cells

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6 July 2018

Investigating human leukemogenesis: from cell lines to in vivo models of human leukemia

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6 July 2018

Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia

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NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.

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Efficient retroviral transduction of human B-lymphoid and myeloid progenitors: marked inhibition of their growth by the Pax5 transgene

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6 July 2018

Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.

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6 July 2018

MLL translocations, histone modifications and leukaemia stem-cell development

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6 July 2018

MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment.

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6 July 2018

Modeling the initiation and progression of human acute leukemia in mice

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6 July 2018

Humanized mice in translational biomedical research

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6 July 2018

Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome

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6 July 2018

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

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6 July 2018

Origins of chromosome translocations in childhood leukaemia

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6 July 2018

Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/γcnull mice model

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6 July 2018

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

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6 July 2018

Genetics of myeloid leukemias

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6 July 2018

The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.

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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

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6 July 2018

New insights to the MLL recombinome of acute leukemias

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21 January 2018

Outcome of risk-based therapy for infant acute lymphoblastic leukemia with or without an MLL gene rearrangement, with emphasis on late effects: a final report of two consecutive studies, MLL96 and MLL98, of the Japan Infant Leukemia Study Group.

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21 January 2018

Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

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Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body

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21 January 2018

Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia.

1 reference

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21 January 2018

Simplified retroviral vector gcsap with murine stem cell virus long terminal repeat allows high and continued expression of enhanced green fluorescent protein by human hematopoietic progenitors engrafted in nonobese diabetic/severe combined immunode

1 reference

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21 January 2018

Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation

1 reference

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21 January 2018

Prenatal and postnatal myeloid cells demonstrate stepwise progression in the pathogenesis of MLL fusion gene leukemia

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Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer

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The analysis of the functions of human B and T cells in humanized NOD/shi-scid/gammac(null) (NOG) mice (hu-HSC NOG mice)

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Activated K-Ras protein accelerates human MLL/AF4-induced leukemo-lymphomogenicity in a transgenic mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0037892

1 reference

Europe PubMed Central

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6 February 2020

2012PLoSO...737892M

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PMC publication ID

1 reference

Europe PubMed Central

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6 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

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6 February 2020

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