Molecular evolution of the Helicobacter pylori vacuolating toxin gene vacA (Q34309390)

1 August 2017

title

Molecular evolution of the Helicobacter pylori vacuolating toxin gene vacA (English)

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Helicobacter pylori infectious disease

1 August 2017

0 references

1 reference

Carrie L Shaffer

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Timothy L Cover

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Sebastian Suerbaum

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1 August 2017

Seth R Bordenstein

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ORCID Public Data File 2021

1 August 2017

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author name string

Kelly A Gangwer

series ordinal

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1 August 2017

D Borden Lacy

series ordinal

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1 August 2017

language of work or name

English

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publication date

24 September 2010

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1 August 2017

published in

Journal of Bacteriology

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1 August 2017

volume

192

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1 August 2017

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1 August 2017

page(s)

6126-6135

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A Global Overview of the Genetic and Functional Diversity in the Helicobacter pylori cag Pathogenicity Island

1 August 2017

cites work

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Host-interactive genes in Amerindian Helicobacter pylori diverge from their Old World homologs and mediate inflammatory responses

6 July 2018

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Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells

6 July 2018

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6 July 2018

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6 July 2018

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Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain

6 July 2018

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Helicobacter pylori evolution: lineage- specific adaptations in homologs of eukaryotic Sel1-like genes

6 July 2018

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6 July 2018

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An African origin for the intimate association between humans and Helicobacter pylori

6 July 2018

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6 July 2018

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Who ate whom? Adaptive Helicobacter genomic changes that accompanied a host jump from early humans to large felines

6 July 2018

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Distinct diversity of vacA, cagA, and cagE genes of Helicobacter pylori associated with peptic ulcer in Japan

6 July 2018

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Functional antagonism between Helicobacter pylori CagA and vacuolating toxin VacA in control of the NFAT signaling pathway in gastric epithelial cells

6 July 2018

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Helicobacter pylori VacA, a paradigm for toxin multifunctionality

6 July 2018

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The Helicobacter pylori vacuolating cytotoxin: from cellular vacuolation to immunosuppressive activities

6 July 2018

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Oncogenic mechanisms of the Helicobacter pylori CagA protein

6 July 2018

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The multiple cellular activities of the VacA cytotoxin of Helicobacter pylori

6 July 2018

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Helicobacter acinonychis: genetic and rodent infection studies of a Helicobacter pylori-like gastric pathogen of cheetahs and other big cats

6 July 2018

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DnaSP, DNA polymorphism analyses by the coalescent and other methods

6 July 2018

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Traces of human migrations in Helicobacter pylori populations

6 July 2018

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Proteome analysis of secreted proteins of the gastric pathogen Helicobacter pylori

6 July 2018

1 reference

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Two distinctive cell binding patterns by vacuolating toxin fused with glutathione S-transferase: one high-affinity m1-specific binding and the other lower-affinity binding for variant m forms

6 July 2018

1 reference

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Helicobacter pylori genetic diversity and risk of human disease

6 July 2018

1 reference

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Differences in genotypes of Helicobacter pylori from different human populations

6 July 2018

1 reference

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Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion

6 July 2018

1 reference

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Vacuolating cytotoxin (vacA) alleles of Helicobacter pylori comprise two geographically widespread types, m1 and m2, and have evolved through limited recombination.

6 July 2018

1 reference

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Full-length sequence analysis of the vacA gene from cytotoxic and noncytotoxic Helicobacter pylori

6 July 2018

1 reference

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Free recombination within Helicobacter pylori

6 July 2018

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The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity.

6 July 2018

1 reference

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Expanding allelic diversity of Helicobacter pylori vacA.

6 July 2018

1 reference

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Prevalence of vacuolating cytotoxin production and distribution of distinct vacA alleles in Helicobacter pylori from China

6 July 2018

1 reference

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Vacuolating toxin production in clinical isolates of Helicobacter pylori with different vacA genotypes

6 July 2018

1 reference

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Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan

6 July 2018

1 reference

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Population genetic analysis of Helicobacter pylori by multilocus enzyme electrophoresis: extensive allelic diversity and recombinational population structure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Adaptive protein evolution at the Adh locus in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Helicobacter pylori Sequences Reflect Past Human Migrations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Importance of EGF receptor, HER2/Neu and Erk1/2 kinase signalling for host cell elongation and scattering induced by the Helicobacter pylori CagA protein: antagonistic effects of the vacuolating cytotoxin VacA.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Using MODELTEST and PAUP* to select a model of nucleotide substitution

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Functional properties of the p33 and p55 domains of the Helicobacter pylori vacuolating cytotoxin.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Helicobacter pyloriInfection

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Evolution of functional polymorphism in the gene coding for the Helicobacter pylori cytotoxin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Genetic variability determinants of Helicobacter pylori: influence of clinical background and geographic origin of isolates

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981223

A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer

28 October 2018

1 reference

12 December 2020

Evolution of bacterial genes: evidences of positive Darwinian selection and fixation of base substitutions in virulence genes of Helicobacter pylori

1 reference

12 December 2020

Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach

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12 December 2020

Geographic distribution of vacA allelic types of Helicobacter pylori

1 reference

12 December 2020

Identifiers

DOI

10.1128/JB.01081-10

1 reference

1 August 2017

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1 August 2017

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