Chemokines in the immunopathogenesis of hepatitis C infection (Q34056271)

30 July 2017

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title

Chemokines in the immunopathogenesis of hepatitis C infection (English)

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30 July 2017

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David H Adams

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30 July 2017

Mathis Heydtmann

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30 July 2017

language of work or name

English

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publication date

1 February 2009

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30 July 2017

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

676-688

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Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.

30 July 2017

cites work

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CCR7 and its ligands: balancing immunity and tolerance

5 July 2018

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Leukocyte adhesion in the liver: distinct adhesion paradigm from other organs

5 July 2018

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Cellular and molecular mechanisms of fibrosis

5 July 2018

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Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients

5 July 2018

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Chemokines and their receptors: drug targets in immunity and inflammation

5 July 2018

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Getting to the site of inflammation: the leukocyte adhesion cascade updated

5 July 2018

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Chemokines in hepatitis C virus infection: pathogenesis, prognosis and therapeutics

5 July 2018

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The role of CCR5/CXCR3 expressing CD8+ cells in liver damage and viral control during persistent hepatitis C virus infection

5 July 2018

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Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

5 July 2018

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Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage

5 July 2018

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Genetics, genomics, and proteomics: implications for the diagnosis and the treatment of chronic hepatitis C.

5 July 2018

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Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells

5 July 2018

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Immunopathogenesis in hepatitis C virus cirrhosis

5 July 2018

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IP-10 predicts viral response and therapeutic outcome in difficult-to-treat patients with HCV genotype 1 infection

5 July 2018

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CXCR3-dependent recruitment of antigen-specific T lymphocytes to the liver during murine cytomegalovirus infection

5 July 2018

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Flying under the radar: the immunobiology of hepatitis C.

5 July 2018

1 reference

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Cellular and molecular mechanisms of liver tolerance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Expression of DC-SIGN and DC-SIGNR on Human Sinusoidal Endothelium

5 July 2018

1 reference

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Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10

5 July 2018

1 reference

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Dendritic cells in a mature age.

5 July 2018

1 reference

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Fas ligand is responsible for CXCR3 chemokine induction in CD4+ T cell-dependent liver damage

5 July 2018

1 reference

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T-cell homing specificity and plasticity: new concepts and future challenges

5 July 2018

1 reference

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Cytokine and chemokine networks: pathways to antiviral defense

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

The hepatitis C envelope 2 protein inhibits LFA-1-transduced protein kinase C signaling for T-lymphocyte migration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Intrahepatic immunity: a tale of two sites?

5 July 2018

1 reference

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Adaptive immune responses in acute and chronic hepatitis C virus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

The CCR5- 32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Nonstructural proteins 4A and 4B of hepatitis C virus transactivate the interleukin 8 promoter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Immunology of hepatitis B virus and hepatitis C virus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

A novel I-TAC promoter polymorphic variant is functional in the presence of replicating HCV in vitro.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Hepatitis C virus NS5A-regulated gene expression and signaling revealed via microarray and comparative promoter analyses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Expression of the CXCR3 ligand I-TAC by hepatocytes in chronic hepatitis C and its correlation with hepatic inflammation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Homing and cellular traffic in lymph nodes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Stromal Cell–Derived Factor-1 from Biliary Epithelial Cells Recruits CXCR4-Positive Cells: Implications for Inflammatory Liver Diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

HCV immunology--death and the maiden T cell.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Nonlinear partial differential equations and applications: Genomic analysis of the host response to hepatitis C virus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Chemokines in liver inflammation and fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Up-regulated expression of fractalkine and its receptor CX3CR1 during liver injury in humans.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Hepatic expression of secondary lymphoid chemokine (CCL21) promotes the development of portal-associated lymphoid tissue in chronic inflammatory liver disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Neighborhood politics: the immunoregulatory function of organ-resident liver endothelial cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Hepatitis C virus infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Noncytolytic control of viral infections by the innate and adaptive immune response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Lymphoid tissue homing chemokines are expressed in chronic inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Chemokine and chemokine receptor interactions provide a mechanism for selective T cell recruitment to specific liver compartments within hepatitis C-infected liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Active participation of CCR5(+)CD8(+) T lymphocytes in the pathogenesis of liver injury in graft-versus-host disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Bystander activation of cytotoxic T cells: studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

A novel migration pathway for rat dendritic cells from the blood: hepatic sinusoids-lymph translocation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Hepatitis C virus replicates in the same immune cell subsets in chronic hepatitis C and occult infection.

5 July 2018

1 reference

Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection

21 January 2018

1 reference

Expansion of hepatitis C-specific CD4+CD25+ regulatory T cells after viral clearance: a mechanism to limit collateral damage?

21 January 2018

1 reference

Detailed analysis of intrahepatic CD8 T cells in the normal and hepatitis C-infected liver reveals differences in specific populations of memory cells with distinct homing phenotypes

21 January 2018

1 reference

Human T cells that are able to produce IL-17 express the chemokine receptor CCR6.

21 January 2018

1 reference

Increased expression of T cell chemokines and their receptors in chronic hepatitis C: relationship with the histological activity of liver disease

21 January 2018

1 reference

Expression of the chemokine IP-10 (CXCL10) by hepatocytes in chronic hepatitis C virus infection correlates with histological severity and lobular inflammation.

21 January 2018

1 reference

Phenotypic and functional characterization of intrahepatic T lymphocytes during chronic hepatitis C.

21 January 2018

1 reference

Liver-infiltrating lymphocytes in end-stage hepatitis C virus: subsets, activation status, and chemokine receptor phenotypes

21 January 2018

1 reference

Expression of chemokine receptors on intrahepatic and peripheral lymphocytes in chronic hepatitis C infection: its relationship to liver inflammation.

21 January 2018

1 reference

Hepatitis C virus core protein and hepatitis activity are associated through transactivation of interleukin-8.

21 January 2018

1 reference

Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells

21 January 2018

1 reference

Structural proteins of Hepatitis C virus induce interleukin 8 production and apoptosis in human endothelial cells

21 January 2018

1 reference

Critical role for CXC chemokine ligand 16 (SR-PSOX) in Th1 response mediated by NKT cells

21 January 2018

1 reference

Hepatitis C virus E2 and CD81 interaction may be associated with altered trafficking of dendritic cells in chronic hepatitis C.

21 January 2018

1 reference

Hepatitis C virus-induced secretion of inflammatory chemokines preferentially recruits NKG2A+CD8+ T cells

21 January 2018

1 reference

Binding of HCV E2 to CD81 induces RANTES secretion and internalization of CC chemokine receptor 5.

21 January 2018

1 reference

Chemokine systems and hepatitis C virus infection: is truth in the genes of the beholders?

21 January 2018

1 reference

Frequency of the HIV-protective CC chemokine receptor 5-Delta32/Delta32 genotype is increased in hepatitis C.

21 January 2018

1 reference

Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C.

21 January 2018

1 reference

CC chemokine receptor 5 delta32 polymorphism in two independent cohorts of hepatitis C virus infected patients without hemophilia

21 January 2018

1 reference

CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation

21 January 2018

1 reference

Involvement of the CXCL12/CXCR4 pathway in the advanced liver disease that is associated with hepatitis C virus or hepatitis B virus

21 January 2018

1 reference

Prospective analysis of effector and regulatory CD4+ T cells in chronic HCV patients undergoing combination antiviral therapy

21 January 2018

1 reference

The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C.

21 January 2018

1 reference

Involvement of chemokines and type 1 cytokines in the pathogenesis of hepatitis C virus-associated mixed cryoglobulinemia vasculitis neuropathy

21 January 2018

1 reference

Signal transduction by the chemokine receptor CXCR3: activation of Ras/ERK, Src, and phosphatidylinositol 3-kinase/Akt controls cell migration and proliferation in human vascular pericytes

21 January 2018

1 reference

Hepatitis C is associated with perturbation of intrahepatic myeloid and plasmacytoid dendritic cell function

21 January 2018

1 reference

The human liver contains multiple populations of NK cells, T cells, and CD3+CD56+ natural T cells with distinct cytotoxic activities and Th1, Th2, and Th0 cytokine secretion patterns

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919201

Differential expression of chemokines and chemokine receptors shapes the inflammatory response in rejecting human liver transplants

28 October 2018

1 reference

12 December 2020

HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication

1 reference

12 December 2020

CCL3/MIP-1alpha is pro-inflammatory in murine T cell-mediated hepatitis by recruiting CCR1-expressing CD4(+) T cells to the liver

1 reference

12 December 2020

Expression of IFN-inducible protein-10 in chronic hepatitis

1 reference

12 December 2020

Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells

1 reference

12 December 2020

CXC chemokine ligand 16 promotes integrin-mediated adhesion of liver-infiltrating lymphocytes to cholangiocytes and hepatocytes within the inflamed human liver

1 reference

12 December 2020

Lymphocyte traffic through sinusoidal endothelial cells is regulated by hepatocytes

1 reference

12 December 2020

Chemokines at large: in-vivo mechanisms of their transport, presentation and clearance

1 reference

12 December 2020

Immune-mediated liver injury

1 reference

12 December 2020

Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells

1 reference

12 December 2020

Coculture of human liver macrophages and cholangiocytes leads to CD40-dependent apoptosis and cytokine secretion

1 reference

12 December 2020

Identifiers

DOI

10.1002/HEP.22763

1 reference

30 July 2017

1 reference

30 July 2017

1 reference