TRIM24 is a p53-induced E3-ubiquitin ligase that undergoes ATM-mediated phosphorylation and autodegradation during DNA damage (Q33899861)

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English	TRIM24 is a p53-induced E3-ubiquitin ligase that undergoes ATM-mediated phosphorylation and autodegradation during DNA damage	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

24820418

retrieved

29 July 2017

title

TRIM24 is a p53-induced E3-ubiquitin ligase that undergoes ATM-mediated phosphorylation and autodegradation during DNA damage (English)

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Europe PubMed Central

PubMed publication ID

24820418

retrieved

29 July 2017

main subject

DNA damage

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author

Aundrietta D Duncan

object named as

Aundrietta D Duncan

series ordinal

3

0 references

Kendra Allton

object named as

Kendra Allton

series ordinal

2

0 references

Abhinav K Jain

object named as

Abhinav K Jain

series ordinal

1

0 references

Michelle Craig Barton

object named as

Michelle C Barton

series ordinal

4

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publication date

1 July 2014

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stated in

Europe PubMed Central

PubMed publication ID

24820418

retrieved

29 July 2017

published in

Molecular and Cellular Biology

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stated in

Europe PubMed Central

PubMed publication ID

24820418

retrieved

29 July 2017

volume

34

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24820418

retrieved

29 July 2017

issue

14

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stated in

Europe PubMed Central

PubMed publication ID

24820418

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29 July 2017

page(s)

2695-2709

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Europe PubMed Central

PubMed publication ID

24820418

retrieved

29 July 2017

cites work

Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells

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The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity

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5 July 2018

p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells

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5 July 2018

TRIM24 links a non-canonical histone signature to breast cancer

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5 July 2018

Making sense of ubiquitin ligases that regulate p53

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5 July 2018

Regulation of p53: TRIM24 enters the RING.

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5 July 2018

Trim24 targets endogenous p53 for degradation

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5 July 2018

Modes of p53 regulation

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PubMed Central

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5 July 2018

Blinded by the Light: The Growing Complexity of p53

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5 July 2018

Modifications of p53: competing for the lysines

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5 July 2018

A complex barcode underlies the heterogeneous response of p53 to stress

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5 July 2018

p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo

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5 July 2018

Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha

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5 July 2018

Signaling by estrogens

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5 July 2018

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

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5 July 2018

p53 in health and disease

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PubMed Central

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5 July 2018

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

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5 July 2018

Genetic and expression aberrations of E3 ubiquitin ligases in human breast cancer

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5 July 2018

ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage

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PubMed Central

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5 July 2018

The complexity of p53 stabilization and activation

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5 July 2018

p53 ubiquitination: Mdm2 and beyond

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PubMed Central

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5 July 2018

TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097665

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5 July 2018

MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097665

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5 July 2018

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

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PubMed Central

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5 July 2018

The p53 pathway: positive and negative feedback loops

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PubMed Central

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5 July 2018

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage

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5 July 2018

Post-translational modification of p53 in tumorigenesis

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5 July 2018

Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species

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5 July 2018

The ubiquitin ligase COP1 is a critical negative regulator of p53

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PubMed Central

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5 July 2018

Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation

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PubMed Central

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5 July 2018

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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5 July 2018

A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter

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5 July 2018

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

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PubMed Central

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5 July 2018

ATM and related protein kinases: safeguarding genome integrity

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PubMed Central

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5 July 2018

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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PubMed Central

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5 July 2018

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

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PubMed Central

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5 July 2018

The tripartite motif family identifies cell compartments

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PubMed Central

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5 July 2018

Surfing the p53 network

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PubMed Central

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5 July 2018

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

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PubMed Central

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5 July 2018

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

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5 July 2018

Enhanced phosphorylation of p53 by ATM in response to DNA damage

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PubMed Central

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5 July 2018

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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5 July 2018

Regulation of p53 stability by Mdm2

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5 July 2018

Mdm2 promotes the rapid degradation of p53

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PubMed Central

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5 July 2018

Expression of the mutated p53 tumor suppressor protein and its molecular and biochemical characterization in multidrug resistant MCF-7/Adr human breast cancer cells

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5 July 2018

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors

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5 July 2018

Estrogen receptors: bioactivities and interactions with cell signaling pathways

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PubMed Central

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5 July 2018

mdm2 expression is induced by wild type p53 activity

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PubMed Central

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5 July 2018

The p53-mdm-2 autoregulatory feedback loop

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PubMed Central

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5 July 2018

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

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5 July 2018

Participation of p53 protein in the cellular response to DNA damage

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PubMed Central

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5 July 2018

Levels of p53 protein increase with maturation in human hematopoietic cells

1 reference

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PubMed Central

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5 July 2018

Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo.

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097665

retrieved

29 October 2018

Identifiers

DOI

10.1128/MCB.01705-12

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24820418

retrieved

29 July 2017

PMC publication ID

4097665

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24820418

retrieved

29 July 2017

PubMed publication ID

24820418

1 reference

stated in

Europe PubMed Central

PubMed publication ID

24820418

retrieved

29 July 2017

 

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