Binding of 7-methoxy-4-(aminomethyl)-coumarin to wild-type and W128F mutant cytochrome P450 2D6 studied by time-resolved fluorescence spectroscopy (Q33224153)

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Language	Label	Description	Also known as
English	Binding of 7-methoxy-4-(aminomethyl)-coumarin to wild-type and W128F mutant cytochrome P450 2D6 studied by time-resolved fluorescence spectroscopy	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Binding of 7-methoxy-4-(aminomethyl)-coumarin to wild-type and W128F mutant cytochrome P450 2D6 studied by time-resolved fluorescence spectroscopy (English)

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Chris Oostenbrink

3

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Europe PubMed Central

PubMed publication ID

24 July 2017

object named as

Chris De Graaf

4

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author name string

Aike Stortelder

1

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Europe PubMed Central

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17 October 2017

Peter H J Keizers

2

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Europe PubMed Central

PMC publication ID

17 October 2017

Petra De Kruijf

5

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Nico P E Vermeulen

6

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Europe PubMed Central

PMC publication ID

17 October 2017

Cees Gooijer

7

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Europe PubMed Central

PMC publication ID

17 October 2017

Jan N M Commandeur

8

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Europe PubMed Central

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17 October 2017

Gert Van der Zwan

9

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Europe PubMed Central

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17 October 2017

publication date

1 February 2006

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17 October 2017

Biochemical Journal

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17 October 2017

393

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Europe PubMed Central

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17 October 2017

Pt 3

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Europe PubMed Central

PMC publication ID

17 October 2017

635-643

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Cytochrome p450 in silico: an integrative modeling approach.

1 reference

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Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future

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Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry

1 reference

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An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution

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THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

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Crystal structure of human cytochrome P450 2C9 with bound warfarin

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Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes

1 reference

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Influence of solvent and substituent on excited state characteristics of laser grade coumarin dyes

1 reference

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Evaluation of a novel high-throughput assay for cytochrome P450 2D6 using 7-methoxy-4-(aminomethyl)-coumarin

1 reference

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How do substrates enter and products exit the buried active site of cytochrome P450cam? 1. Random expulsion molecular dynamics investigation of ligand access channels and mechanisms.

1 reference

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21 June 2018

Design, synthesis, and characterization of 7-methoxy-4-(aminomethyl)coumarin as a novel and selective cytochrome P450 2D6 substrate suitable for high-throughput screening

1 reference

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Intrinsic fluorescence of hemoglobins and myoglobins

1 reference

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1La and 1Lb transitions of tryptophan: applications of theory and experimental observations to fluorescence of proteins

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Development and validation of a genetic algorithm for flexible docking

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Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

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Picosecond fluorescence decay of tryptophans in myoglobin

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The interpretation of protein structures: Estimation of static accessibility

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Time-resolved fluorescence of proteins

1 reference

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Global analysis of biochemical and biophysical data

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21 June 2018

Exposure of tryptophanyl residues in proteins. Quantitative determination by fluorescence quenching studies

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Metabolic regio- and stereoselectivity of cytochrome P450 2D6 towards 3,4-methylenedioxy-N-alkylamphetamines: in silico predictions and experimental validation.

1 reference

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31 October 2018

Influence of phenylalanine 120 on cytochrome P450 2D6 catalytic selectivity and regiospecificity: crucial role in 7-methoxy-4-(aminomethyl)-coumarin metabolism

1 reference

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31 October 2018

The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

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Role of protein and substrate dynamics in catalysis by Pseudomonas putida cytochrome P450cam

1 reference

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How do substrates enter and products exit the buried active site of cytochrome P450cam? 2. Steered molecular dynamics and adiabatic mapping of substrate pathways.

1 reference

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31 October 2018

Identifiers

10.1042/BJ20051169

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

ResearchGate publication ID

0 references

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