Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2 (Q30981876)

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English	Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2	scientific article

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21049984%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2 (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21049984%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

prostaglandin E2 1-glyceryl ester

1 reference

ChEBI release 2020-05-28

Carboxylesterase 2

1 reference

GOA release 2020-03-11

carboxylic ester hydrolase activity

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

Philip M Potter

5

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15 January 2020

author name string

Shuqi Xie

1

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15 January 2020

Abdolsamad Borazjani

2

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15 January 2020

M Jason Hatfield

3

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15 January 2020

Carol C Edwards

4

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15 January 2020

Matthew K Ross

6

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15 January 2020

publication date

1 December 2010

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15 January 2020

Chemical Research in Toxicology

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15 January 2020

23

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15 January 2020

12

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15 January 2020

1890-1904

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15 January 2020

Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin

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Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells

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Macrophage cholesteryl ester mobilization and atherosclerosis

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Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism

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Human carboxylesterases: an update on CES1, CES2 and CES3.

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Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

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28 July 2018

Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages.

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Targeting the endocannabinoid system: to enhance or reduce?

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28 July 2018

Activation of the endocannabinoid system by organophosphorus nerve agents

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28 July 2018

Prostaglandin E2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFkappaB activity

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28 July 2018

Non-redundant functions of cyclooxygenases: oxygenation of endocannabinoids

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A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol

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28 July 2018

Human carboxylesterases and their role in xenobiotic and endobiotic metabolism

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28 July 2018

Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1.

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Hydrolytic metabolism of pyrethroids by human and other mammalian carboxylesterases

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Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2.

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The glyceryl ester of prostaglandin E2 mobilizes calcium and activates signal transduction in RAW264.7 cells

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The molecular logic of endocannabinoid signalling

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Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition

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Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2.

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Identifiers

10.1021/TX1002194

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15 January 2020

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15 January 2020

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15 January 2020

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