Structure of a bacterial multidrug ABC transporter (Q29617308)

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29 December 2019

title

Structure of a bacterial multidrug ABC transporter (English)

2 references

PubMed

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29 December 2019

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29 December 2019

Kaspar P Locher

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29 December 2019

language of work or name

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30 April 2017

publication date

30 August 2006

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29 December 2019

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30 April 2017

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29 December 2019

volume

443

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30 April 2017

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29 December 2019

issue

7108

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29 December 2019

page(s)

180-185

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Overview: ABC transporters and human disease

29 December 2019

cites work

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Structure and function of the CFTR chloride channel

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The transporter associated with antigen processing: function and implications in human diseases

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A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene

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ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans

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Reconstitution of Drug Transport by Purified P-glycoprotein

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The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism

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7 January 2021

Three-dimensional structure of P-glycoprotein: the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state.

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Projection structure of P-glycoprotein by electron microscopy. Evidence for a closed conformation of the nucleotide binding domains

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Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing

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Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

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ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

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Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites

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CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains

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P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites.

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7 January 2021

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

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Glycerol facilitator GlpF and the associated aquaporin family of channels

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7 January 2021

Structural comparison of lactose permease and the glycerol-3-phosphate antiporter: members of the major facilitator superfamily

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7 January 2021

An atomic detail model for the human ATP binding cassette transporter P‐glycoprotein derived from disulphide cross‐ linking and homology modeling

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7 January 2021

RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters

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7 January 2021

Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation

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7 January 2021

RETRACTED: Structure of the ABC transporter MsbA in complex with ADP.vanadate and lipopolysaccharide

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7 January 2021

Effect of cystic fibrosis-associated mutations in the fourth intracellular loop of cystic fibrosis transmembrane conductance regulator.

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7 January 2021

3D domain swapping: as domains continue to swap

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7 January 2021

Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle

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7 January 2021

Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

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7 January 2021

The ATP switch model for ABC transporters

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7 January 2021

Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux.

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7 January 2021

Simple Allosteric Model for Membrane Pumps

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7 January 2021

The ATP/substrate stoichiometry of the ATP-binding cassette (ABC) transporter OpuA.

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7 January 2021

Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein

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7 January 2021

Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities

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7 January 2021

Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).

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7 January 2021

Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters

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7 January 2021

A Tweezers-like Motion of the ATP-Binding Cassette Dimer in an ABC Transport Cycle

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7 January 2021

Demonstration of conformational changes associated with activation of the maltose transport complex

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7 January 2021

Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic fibrosis gene

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The spectrum of cystic fibrosis mutations

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Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure

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7 January 2021

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Identifiers

3 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

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Dimensions Publication ID

29 December 2019

1046978650

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

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3 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

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