Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway (Q28507891)

24 January 2017

title

Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway (English)

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H-2 class II histocompatibility antigen, A-D beta chain

24 January 2017

main subject

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H-2 class II histocompatibility antigen, A-K alpha chain

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CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

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Class II histocompatibility antigen, M alpha chain

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H. Ploegh

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24 January 2017

T. Miyazaki

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24 January 2017

P. Wolf

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24 January 2017

S. Tourne

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24 January 2017

C. Waltzinger

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24 January 2017

A. Dierich

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24 January 2017

N. Barois

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24 January 2017

C. Benoist

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24 January 2017

D. Mathis

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24 January 2017

language of work or name

English

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publication date

23 February 1996

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24 January 2017

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24 January 2017

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24 January 2017

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24 January 2017

page(s)

531–541

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In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides

24 January 2017

cites work

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Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression

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Another view of the selective model of thymocyte selection.

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A cluster of transcribed sequences between the Pb and Ob genes of the murine major histocompatibility complex

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New class II-like genes in the murine MHC.

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Mice lacking MHC class II molecules

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Assembly, transport, and function of MHC class II molecules

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HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

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Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells

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HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

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MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

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Positive selection of thymocytes

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Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells

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A new human HLA class II-related locus, DM

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Self-release of CLIP in peptide loading of HLA-DR molecules

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Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes

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7 January 2021

Kinetics of the reactions between the invariant chain (85-99) peptide and proteins of the murine class II MHC.

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7 January 2021

Supermotifs enable natural invariant chain-derived peptides to interact with many major histocompatibility complex-class II molecules

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7 January 2021

Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes

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A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex

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An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

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7 January 2021

Potent effects of low levels of MHC class II-associated invariant chain on CD4+ T cell development

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7 January 2021

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

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7 January 2021

Sequence analysis of peptides bound to MHC class II molecules

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7 January 2021

A role for peptide in determining MHC class II structure

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7 January 2021

Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments

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7 January 2021

Invariant chain peptides in most HLA-DR molecules of an antigen-processing mutant

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7 January 2021

Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.

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7 January 2021

Reconstitution of invariant chain function in transgenic mice in vivo by individual p31 and p41 isoforms

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7 January 2021

DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide

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7 January 2021

Mediation by HLA-DM of dissociation of peptides from HLA-DR

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7 January 2021

The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent.

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7 January 2021

The influence of invariant chain on the positive selection of single T cell receptor specificities

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7 January 2021

Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH

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7 January 2021

Mice lacking the MHC class II-associated invariant chain

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7 January 2021

How MHC class II molecules acquire peptide cargo: biosynthesis and trafficking through the endocytic pathway

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7 January 2021