Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis (Q27323098)

From Wikidata

Jump to navigation Jump to search

The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.

scientific article

Language	Label	Description	Also known as
English	Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis	scientific article

Statements

scholarly article

0 references

Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis (English)

0 references

0 references

1 reference

based on heuristic

inferred from title

reactive oxygen species

1 reference

based on heuristic

inferred from title

author name string

David Freeman

1

author given names

David

author last names

Freeman

1 reference

PubMed publication ID

19 October 2023

Rudy Cedillos

2

author given names

Rudy

author last names

Cedillos

1 reference

PubMed publication ID

19 October 2023

Samantha Choyke

3

author given names

Samantha

author last names

Choyke

1 reference

PubMed publication ID

19 October 2023

Zana Lukic

4

author given names

Zana

author last names

Lukic

1 reference

PubMed publication ID

19 October 2023

Kathleen McGuire

5

author given names

Kathleen

author last names

McGuire

1 reference

PubMed publication ID

19 October 2023

Shauna Marvin

6

author given names

Shauna

author last names

Marvin

1 reference

PubMed publication ID

19 October 2023

Andrew M Burrage

7

author given names

Andrew M

author last names

Burrage

1 reference

PubMed publication ID

19 October 2023

Stacey Sudholt

8

author given names

Stacey

author last names

Sudholt

1 reference

PubMed publication ID

19 October 2023

Ajay Rana

9

author given names

Ajay

author last names

Rana

1 reference

PubMed publication ID

19 October 2023

Christopher O'Connor

10

0 references

Christopher M Wiethoff

11

author given names

Christopher M

author last names

Wiethoff

1 reference

PubMed publication ID

19 October 2023

Edward M Campbell

12

author given names

Edward M

author last names

Campbell

1 reference

PubMed publication ID

19 October 2023

language of work or name

0 references

publication date

2013

0 references

0 references

8

0 references

4

0 references

e62143

0 references

copyright license

Creative Commons Attribution 4.0 International

25 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

21 March 2017

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

21 March 2017

Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

21 March 2017

A capsid-encoded PPxY-motif facilitates adenovirus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

21 March 2017

The inflammasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

21 March 2017

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

21 March 2017

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

21 March 2017

Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

21 March 2017

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

21 March 2017

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

7 April 2017

Parkinson's disease: mechanisms and models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

7 April 2017

Inflammasomes in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

7 April 2017

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

7 April 2017

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

7 April 2017

Lysosome-dependent pathways as a unifying theme in Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Exosomal cell-to-cell transmission of alpha synuclein oligomers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Spatiotemporal dynamics of adenovirus membrane rupture and endosomal escape

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Lysosomal pathways to cell death and their therapeutic applications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Membrane curvature sensing by amphipathic helices: a single liposome study using α-synuclein and annexin B12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

When galectins recognize glycans: from biochemistry to physiology and back again

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Adenovirus type 5 rupture of lysosomes leads to cathepsin B-dependent mitochondrial stress and production of reactive oxygen species.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

A deadly spread: cellular mechanisms of α-synuclein transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

In vivo demonstration that alpha-synuclein oligomers are toxic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Lysosomal localization and mechanism of membrane penetration influence nonenveloped virus activation of the NLRP3 inflammasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Adenovirus membrane penetration activates the NLRP3 inflammasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

A new wave of cellular imaging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

An N-terminal domain of adenovirus protein VI fragments membranes by inducing positive membrane curvature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Galectin-3, a marker for vacuole lysis by invasive pathogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

The influence of microglia on the pathogenesis of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Lysosomal membrane permeabilization in cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Wild-type alpha-synuclein interacts with pro-apoptotic proteins PKCdelta and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Intravesicular localization and exocytosis of alpha-synuclein and its aggregates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Adenovirus protein VI mediates membrane disruption following capsid disassembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

The interaction between the fiber knob domain and the cellular attachment receptor determines the intracellular trafficking route of adenoviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

28 September 2017

Cell-to-cell transmission of α-synuclein aggregates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

31 May 2018

Drifting motions of the adenovirus receptor CAR and immobile integrins initiate virus uncoating and membrane lytic protein exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

27 November 2018

Tracking the dynamic interplay between bacterial and host factors during pathogen-induced vacuole rupture in real time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

27 November 2018

Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

27 November 2018

The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

27 November 2018

Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

27 November 2018

Vesicle permeabilization by protofibrillar alpha-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

27 November 2018

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636263

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23634225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23634225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0062143

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2013PLoSO...862143F

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27323098&oldid=1993612879"