Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins (Q26991478)

From Wikidata

Jump to navigation Jump to search

The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.

scientific article

Language	Label	Description	Also known as
English	Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins	scientific article

Statements

scholarly article

1 reference

Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins (English)

1 reference

2

0 references

Jurian Schuijers

object named as

Jurian Schuijers

1

0 references

language of work or name

1 reference

publication date

13 June 2012

1 reference

The EMBO Journal

1 reference

31

1 reference

12

1 reference

2685-96

1 reference

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Coat variation in the domestic dog is governed by variants in three genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Wnt signaling induces epithelial differentiation during cutaneous wound healing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Neonatal lethality of LGR5 null mice is associated with ankyloglossia and gastrointestinal distension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Association of the APC gene product with beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

The R-spondin protein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Generalized lacZ expression with the ROSA26 Cre reporter strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

A common human skin tumour is caused by activating mutations in beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Mutations in R-spondin 4 (RSPO4) underlie inherited anonychia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Identification of stem cells in small intestine and colon by marker gene Lgr5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Crypt stem cells as the cells-of-origin of intestinal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Association of the APC tumor suppressor protein with catenins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Regulation of bone formation and remodeling by G-protein-coupled receptor 48

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

R-spondin3 is required for mouse placental development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Defective postnatal development of the male reproductive tract in LGR4 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Female development in mammals is regulated by Wnt-4 signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

SOX9 is required for the differentiation of paneth cells in the intestinal epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Myc deletion rescues Apc deficiency in the small intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

21 March 2017

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

7 April 2017

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

7 April 2017

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

7 April 2017

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

7 April 2017

Defining the epithelial stem cell niche in skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

7 April 2017

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

7 April 2017

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

7 April 2017

Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

7 April 2017

Three decades of Wnts: a personal perspective on how a scientific field developed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Mutant KRAS promotes hyperplasia and alters differentiation in the colon epithelium but does not expand the presumptive stem cell pool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Intestinal epithelial stem cells do not protect their genome by asymmetric chromosome segregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Leucine-rich repeat-containing G-protein-coupled receptors as markers of adult stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Enteric defensins are essential regulators of intestinal microbial ecology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Loss-of-function point mutations and two-furin domain derivatives provide insights about R-spondin2 structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

G-protein-coupled receptor GPR49 is up-regulated in basal cell carcinoma and promotes cell proliferation and tumor formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

R-Spondin family members regulate the Wnt pathway by a common mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

RSPO4 is the major gene in autosomal-recessive anonychia and mutations cluster in the furin-like cysteine-rich domains of the Wnt signaling ligand R-spondin 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

The Intestinal Wnt/TCF Signature.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

LGR4 regulates the postnatal development and integrity of male reproductive tracts in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

R-spondin1 is essential in sex determination, skin differentiation and malignancy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

The makings of maleness: towards an integrated view of male sexual development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Human sebaceous tumors harbor inactivating mutations in LEF1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

A systematic review and meta-analysis comparing outcome of severely injured patients treated in trauma centers following the establishment of trauma systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

R-Spondin proteins: a novel link to beta-catenin activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Mitogenic influence of human R-spondin1 on the intestinal epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

The pathway to femaleness: current knowledge on embryonic development of the ovary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Signaling at the crossroads of gonad development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Hair follicle stem cells in the lower bulge form the secondary germ, a biochemically distinct but functionally equivalent progenitor cell population, at the termination of catagen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

One tissue, two fates: molecular genetic events that underlie testis versus ovary development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Capturing and profiling adult hair follicle stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Overexpression of orphan G-protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with beta-catenin mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Cloning and identification of a cDNA that encodes a novel human protein with thrombospondin type I repeat domain, hPWTSR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

The intestinal epithelial stem cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Characterization of two fly LGR (leucine-rich repeat-containing, G protein-coupled receptor) proteins homologous to vertebrate glycoprotein hormone receptors: constitutive activation of wild-type fly LGR1 but not LGR2 in transfected mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

The nematode leucine-rich repeat-containing, G protein-coupled receptor (LGR) protein homologous to vertebrate gonadotropin and thyrotropin receptors is constitutively active in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

The oncogenic activation of beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Molecular cloning of a novel, putative G protein-coupled receptor from sea anemones structurally related to members of the FSH, TSH, LH/CG receptor family from mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

A G protein-coupled receptor with low density lipoprotein-binding motifs suggests a role for lipoproteins in G-linked signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 September 2017

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

31 May 2018

A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

31 May 2018

Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

31 May 2018

Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

31 May 2018

G protein-coupled receptor 48 upregulates estrogen receptor alpha expression via cAMP/PKA signaling in the male reproductive tract.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

31 May 2018

Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

31 May 2018

Expression of leucine-rich repeat-containing G-protein-coupled receptors in the human cyclic endometrium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

31 May 2018

Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

31 May 2018

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. I. Columnar cell.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

31 May 2018

Male development of chromosomally female mice transgenic for Sry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

31 May 2018

Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Molecular cloning, genomic organization, and developmental regulation of a novel receptor from Drosophila melanogaster structurally related to members of the thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone/choriogonado

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

The Three Subfamilies of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors (LGR): Identification of LGR6 and LGR7 and the Signaling Mechanism for LGR7

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

GPR48 regulates epithelial cell proliferation and migration by activating EGFR during eyelid development

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Isolation and in vitro expansion of human colonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Dickkopf 1 promotes regression of hair follicles

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Leucine-rich repeat-containing, G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4.

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Dynamic expression of R-spondin family genes in mouse development.

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Differential expression and localization of WNTs in an animal model of skin wound healing.

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse.

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Defective development of the gall bladder and cystic duct in Lgr4- hypomorphic mice.

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.149

21 January 2018

Molecular characterization of a new leucine-rich repeat-containing G protein-coupled receptor from a bivalve mollusc: evolutionary implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 November 2018

Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380219

28 November 2018

Eye-open at birth phenotype with reduced keratinocyte motility in LGR4 null mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22617424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/22617424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Examining the Role of Paneth Cells in the Small Intestine by Lineage Ablation in Transgenic Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22617424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22617424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rspo3 Binds Syndecan 4 and Induces Wnt/PCP Signaling via Clathrin-Mediated Endocytosis to Promote Morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22617424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leucine-rich repeat-containing G protein-coupled receptor-4 (LGR4, Gpr48) is essential for renal development in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22617424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22617424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/EMBOJ.2012.149

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q26991478&oldid=1958281164"