The miR-205-5p/BRCA1/RAD17 Axis Promotes Genomic Instability in Head and Neck Squamous Cell Carcinomas (Q90080210)

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scientific article published on 11 September 2019

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English	The miR-205-5p/BRCA1/RAD17 Axis Promotes Genomic Instability in Head and Neck Squamous Cell Carcinomas	scientific article published on 11 September 2019

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514456%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

The miR-205-5p/BRCA1/RAD17 Axis Promotes Genomic Instability in Head and Neck Squamous Cell Carcinomas (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514456%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

1

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11 April 2020

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514456%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

Silvia Di Agostino

7

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11 April 2020

author name string

Federica Ganci

3

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11 April 2020

Giuseppe Grasso

4

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11 April 2020

Sabrina Strano

5

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11 April 2020

Giovanni Blandino

6

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11 April 2020

publication date

11 September 2019

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11 April 2020

1 reference

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11 April 2020

11

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11 April 2020

9

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11 April 2020

copyright license

Creative Commons Attribution 4.0 International

11 September 2019

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April 2022 Public Data File from Crossref

copyright status

0 references

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Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells

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A mammalian microRNA expression atlas based on small RNA library sequencing

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MicroRNAs in tumorigenesis: a primer

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An oncogene-induced DNA damage model for cancer development

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MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia

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MicroRNA regulation of DNA repair gene expression in hypoxic stress

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miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon.

1 reference

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microRNA-205 regulates HER3 in human breast cancer

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miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells

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The DNA-damage response in human biology and disease

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A putative role for microRNA-205 in mammary epithelial cell progenitors

1 reference

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Genomic instability--an evolving hallmark of cancer

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Molecular analysis of surgical margins in head and neck cancer: more than a marginal issue.

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Expression of microRNAs in squamous cell carcinoma of human head and neck and the esophagus: miR-205 and miR-21 are specific markers for HNSCC and ESCC.

1 reference

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Live cell imaging of micronucleus formation and development

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53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

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Allelic expression imbalance of TP53 mutated and polymorphic alleles in head and neck tumors

1 reference

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Links between mutant p53 and genomic instability

1 reference

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MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

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A role for small RNAs in DNA double-strand break repair.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

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p53 mutations in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

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MiR-205 in cancer: an angel or a devil?

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

12 December 2020

based on heuristic

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Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of TP53 mutation-associated microRNAs predicts clinical outcome in head and neck squamous cell carcinoma patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational landscape and significance across 12 major cancer types

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

12 December 2020

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High-throughput sequencing of small RNA transcriptomes reveals critical biological features targeted by microRNAs in cell models used for squamous cell cancer research.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

12 December 2020

based on heuristic

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MicroRNAs and the cancer phenotype: profiling, signatures and clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

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Insights into the diverse roles of miR-205 in human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

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Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/31514456

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Defects in the Fanconi Anemia Pathway and Chromatid Cohesion in Head and Neck Cancer

1 reference

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Predicting effective microRNA target sites in mammalian mRNAs

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Evaluation of spheroid head and neck squamous cell carcinoma cell models in comparison to monolayer cultures

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Upregulation of MiR-205 transcriptionally suppresses SMAD4 and PTEN and contributes to human ovarian cancer progression

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Altered peritumoral microRNA expression predicts head and neck cancer patients with a high risk of recurrence.

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53BP1 and BRCA1 control pathway choice for stalled replication restart

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Characteristic miRNA expression signature and random forest survival analysis identify potential cancer-driving miRNAs in a broad range of head and neck squamous cell carcinoma subtypes

1 reference

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The molecular landscape of head and neck cancer.

1 reference

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Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma.

1 reference

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inferred from PubMed ID database lookup

miRWalk: An online resource for prediction of microRNA binding sites

1 reference

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miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition

1 reference

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The Role of MicroRNAs in Recurrence and Metastasis of Head and Neck Squamous Cell Carcinoma

1 reference

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Identifiers

10.3390/CANCERS11091347

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514456%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514456%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31514456%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

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