Rac is required for constitutive macropinocytosis by dendritic cells but does not control its downregulation. (Q52166799)

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scientific article published in July 2000

Language	Label	Description	Also known as
English	Rac is required for constitutive macropinocytosis by dendritic cells but does not control its downregulation.	scientific article published in July 2000

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

Rac is required for constitutive macropinocytosis by dendritic cells but does not control its downregulation. (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

1 reference

based on heuristic

inferred from title

macropinocytosis

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based on heuristic

inferred from title

Eeva-Liisa Eskelinen

3

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

4

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

5

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

author name string

West MA

1

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

Prescott AR

2

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

language of work or name

0 references

publication date

1 July 2000

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

Current Biology

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

10

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

14

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

839-848

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

Dendritic cells and the control of immunity

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Antigen processing for amateurs and professionals

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The endocytic activity of dendritic cells.

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Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products

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Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells

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Macropinocytosis

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Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

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The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts

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The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.

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Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid

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Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

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Fc receptor-mediated phagocytosis requires CDC42 and Rac1.

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The biochemical basis of the NADPH oxidase of phagocytes.

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Effectors for the Rho GTPases

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Membrane ruffling, macropinocytosis and antigen presentation in the absence of gelsolin in murine dendritic cells

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Contrasting effects of TGF-beta 1 and TNF-alpha on the development of dendritic cells from progenitors in mouse bone marrow

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

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Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability

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The role of dendritic cells in the induction and regulation of immunity to microbial infection.

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Identifiers

10.1016/S0960-9822(00)00595-9

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/10899002

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