Mixed results with modulation of TH-17 cells in human autoimmune diseases (Q46204430)

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scientific article

Language	Label	Description	Also known as
English	Mixed results with modulation of TH-17 cells in human autoimmune diseases	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/20016509

Mixed results with modulation of TH-17 cells in human autoimmune diseases (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/20016509

author name string

Lawrence Steinman

1

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/20016509

language of work or name

0 references

publication date

17 December 2009

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/20016509

Nature Immunology

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/20016509

11

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/20016509

1

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/20016509

41-44

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/20016509

Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2.

1 reference

https://api.crossref.org/works/10.1038%2FNI.1803

21 January 2018

Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNI.1803

21 January 2018

Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system

1 reference

https://api.crossref.org/works/10.1038%2FNI.1803

21 January 2018

Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4+ T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNI.1803

21 January 2018

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic and functional features of human Th17 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma osteopontin levels in multiple sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T(H)-17 cells in the circle of immunity and autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why did IL-12/IL-23 antibody therapy fail in multiple sclerosis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rush to judgment on Th17

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primer: inflammasomes and interleukin 1beta in inflammatory disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory effects of IFN-beta on production of osteopontin and IL-17 by CD4+ T Cells in MS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and signalling in the IL-17 receptor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of ongoing disease in a nonhuman primate model of multiple sclerosis by a human-anti-human IL-12p40 antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated osteopontin levels in active relapsing-remitting multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shifting therapeutic attention in MS to osteopontin, type 1 and type 2 IFN

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF neutralization in MS: results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A molecular trio in relapse and remission in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy: Targeted but not trouble-free: efalizumab and PML

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design of effective immunotherapy for human autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-23/IL-17 immunity as a hallmark of Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Humanized antihuman IL-6 receptor antibody, tocilizumab

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple sclerosis: a two-stage disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-interleukin-12 antibody for active Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-bet is essential for encephalitogenicity of both Th1 and Th17 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20016509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NI.1803

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/20016509

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/20016509

ResearchGate publication ID

0 references

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