Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice (Q44437509)

3 December 2017

title

Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice (English)

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3 December 2017

Harry T Orr

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Huda Y Zoghbi

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Effat S Emamian

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3 December 2017

Michael D Kaytor

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3 December 2017

Lisa A Duvick

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3 December 2017

Tao Zu

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3 December 2017

Susan K Tousey

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3 December 2017

H Brent Clark

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3 December 2017

language of work or name

English

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publication date

1 May 2003

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3 December 2017

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3 December 2017

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3 December 2017

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3 December 2017

page(s)

375-387

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Identification and characterization of the gene causing type 1 spinocerebellar ataxia

3 December 2017

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Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

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Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

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Neuronal intranuclear inclusions in polyglutamine diseases: nuclear weapons or nuclear fallout?

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7 January 2021

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice

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Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1.

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Beyond the Qs in the polyglutamine diseases

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Structural and immunocytochemical features of olivopontocerebellar atrophy caused by the spinocerebellar ataxia type 1 (SCA-1) mutation define a unique phenotype

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Intranuclear neuronal inclusions: a common pathogenic mechanism for glutamine-repeat neurodegenerative diseases?

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7 January 2021

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

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7 January 2021

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7 January 2021

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Identifiers

DOI

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3 December 2017

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