Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall (Q42019558)

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scientific article published on 18 November 2008

Language	Label	Description	Also known as
English	Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall	scientific article published on 18 November 2008

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

author name string

Godfrey S Getz

1

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Catherine A Reardon

2

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

18 November 2008

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Journal of Lipid Research

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

50 Suppl

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

S156-61

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Regulation of endogenous apolipoprotein E secretion by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Impact of apoE genotype on oxidative stress, inflammation and disease risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipoprotein E-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Nutritional regulation of adipose tissue apolipoprotein E expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Adipose tissue and atherosclerosis: exploring the connection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Putting cholesterol in its place: apoE and reverse cholesterol transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Apolipoprotein E recycling: implications for dyslipidemia and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Distinct cellular loci for the ABCA1-dependent and ABCA1-independent lipid efflux mediated by endogenous apolipoprotein E expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Apolipoprotein-mediated pathways of lipid antigen presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

The key role of apolipoprotein E in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Apolipoprotein E is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Distinct signaling mechanisms for apoE inhibition of cell migration and proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Divergent effects of peroxisome proliferator-activated receptor gamma agonists and tumor necrosis factor alpha on adipocyte ApoE expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Contributions of domain structure and lipid interaction to the functionality of exchangeable human apolipoproteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Antimitogenic effects of HDL and APOE mediated by Cox-2-dependent IP activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Enlargement of high density lipoprotein in mice via liver X receptor activation requires apolipoprotein E and is abolished by cholesteryl ester transfer protein expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

VLDL induces adipocyte differentiation in ApoE-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Lipoprotein modulation of subendothelial heparan sulfate proteoglycans (perlecan) and atherogenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Reduction of isoprostanes and regression of advanced atherosclerosis by apolipoprotein E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Low levels of extrahepatic nonmacrophage ApoE inhibit atherosclerosis without correcting hypercholesterolemia in ApoE-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Apolipoprotein E and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Decreased selective uptake of high density lipoprotein cholesteryl esters in apolipoprotein E knock-out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

5 June 2018

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

Structure-function properties of the apoE-dependent COX-2 pathway in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

A pathway-dependent on apoE, ApoAI, and ABCA1 determines formation of buoyant high-density lipoprotein by macrophage foam cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

Apolipoprotein E suppresses the type I inflammatory response in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

The receptor binding domain of apolipoprotein E is responsible for its antioxidant activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

Apolipoprotein E promotes the regression of atherosclerosis independently of lowering plasma cholesterol levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

Generation of a recombinant apolipoprotein E variant with improved biological functions: hydrophobic residues (LEU-261, TRP-264, PHE-265, LEU-268, VAL-269) of apoE can account for the apoE-induced hypertriglyceridemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

Subphysiologic apolipoprotein E (ApoE) plasma levels inhibit neointimal formation after arterial injury in ApoE-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

Apolipoprotein E modulates immune activation by acting on the antigen-presenting cell.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

Hepatocyte-derived ApoE is more effective than non-hepatocyte-derived ApoE in remnant lipoprotein clearance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

Hepatic expression of apolipoprotein E inhibits progression of atherosclerosis without reducing cholesterol levels in LDL receptor-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674757

17 August 2018

Endogenous ApoE expression modulates adipocyte triglyceride content and turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/19018038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of apolipoprotein E in excess fat accumulation and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19018038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E interrupts interleukin-1beta signaling in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19018038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/19018038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of apolipoprotein E3 in transgenic rabbits causes combined hyperlipidemia by stimulating hepatic VLDL production and impairing VLDL lipolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19018038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and platelet-activating factor acetylhydrolase in atherosclerosis-susceptible mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19018038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extrahepatic synthesis of apolipoprotein E

1 reference

https://pubmed.ncbi.nlm.nih.gov/19018038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage free cholesterol content regulates apolipoprotein E synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19018038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1194/JLR.R800058-JLR200

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

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