LEDGF/p75 Deficiency Increases Deletions at the HIV-1 cDNA Ends (Q40038972)

6 October 2017

LEDGF/p75 Deficiency Increases Deletions at the HIV-1 cDNA Ends (English)

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6 October 2017

Murilo T D Bueno

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6 October 2017

Daniel Reyes

series ordinal

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6 October 2017

Manuel Llano

series ordinal

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6 October 2017

language of work or name

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15 September 2017

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6 October 2017

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6 October 2017

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6 October 2017

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Creative Commons Attribution 4.0 International

6 October 2017

start time

15 September 2017

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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17 June 2018

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Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration

17 June 2018

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HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells

17 June 2018

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HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor

17 June 2018

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Host protein Ku70 binds and protects HIV-1 integrase from proteasomal degradation and is required for HIV replication

17 June 2018

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XPB mediated retroviral cDNA degradation coincides with entry to the nucleus.

17 June 2018

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LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors

17 June 2018

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The SET complex acts as a barrier to autointegration of HIV-1

17 June 2018

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Viral complementation allows HIV-1 replication without integration

17 June 2018

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LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

17 June 2018

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An essential role for LEDGF/p75 in HIV integration

17 June 2018

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Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function

17 June 2018

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The DNA repair genes XPB and XPD defend cells from retroviral infection

17 June 2018

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Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus

17 June 2018

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Suppression of retroviral infection by the RAD52 DNA repair protein

17 June 2018

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Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions

17 June 2018

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Mutations in the 5′ End of the Human Immunodeficiency Virus Type 1 Polypurine Tract Affect RNase H Cleavage Specificity and Virus Titer

17 June 2018

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Human immunodeficiency virus type 1 nucleocapsid zn(2+) fingers are required for efficient reverse transcription, initial integration processes, and protection of newly synthesized viral DNA.

17 June 2018

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Effect of Ku80 depletion on the preintegrative steps of HIV-1 replication in human cells

17 June 2018

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Mutations in the RNase H domain of HIV-1 reverse transcriptase affect the initiation of DNA synthesis and the specificity of RNase H cleavage in vivo.

17 June 2018

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Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection

17 June 2018

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A quantitative assay for HIV DNA integration in vivo

17 June 2018

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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

17 June 2018

1 reference

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Characterization of the block in replication of nucleocapsid protein zinc finger mutants from moloney murine leukemia virus.

17 June 2018

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The accuracy of reverse transcriptase from HIV-1.

17 June 2018

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Analysis of long terminal repeat circle junctions of human immunodeficiency virus type 1.

17 June 2018

1 reference

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Circular DNA of human immunodeficiency virus: analysis of circle junction nucleotide sequences

17 June 2018

1 reference

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Human immunodeficiency virus reverse transcriptase ribonuclease H: specificity of tRNALys3-primer excision

17 June 2018

1 reference

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Sequence of the circle junction of human immunodeficiency virus type 1: implications for reverse transcription and integration

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5618025

Analysis of human immunodeficiency virus type 1 LTR-LTR junctions in peripheral blood mononuclear cells of infected individuals

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5618025

Specificity of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H in removal of the minus-strand primer, tRNA(Lys3)

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5618025

Incomplete removal of the RNA primer for minus-strand DNA synthesis by human immunodeficiency virus type 1 reverse transcriptase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5618025

Retroviral Reverse Transcription and Integration: Progress and Problems

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5618025

Evolution of 2-long terminal repeat (2-LTR) episomal HIV-1 DNA in raltegravir-treated patients and in in vitro infected cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5618025

Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5618025

20 August 2018

Identifiers

DOI

10.3390/V9090259

1 reference

6 October 2017

1 reference

6 October 2017

PubMed publication ID

28914817

1 reference