Entry |
|
Symbol |
HADH
|
Name |
3-hydroxyacyl-CoA dehydrogenase [EC: 1.1.1.35]
|
Pathway |
map00280 | Valine, leucine and isoleucine degradation |
map00907 | Pinene, camphor and geraniol degradation |
map01110 | Biosynthesis of secondary metabolites |
map01120 | Microbial metabolism in diverse environments |
|
Module |
M00032 | Lysine degradation, lysine => saccharopine => acetoacetyl-CoA |
M00085 | Fatty acid elongation in mitochondria |
|
Reaction |
R01778 | (3S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase |
R01975 | (S)-3-hydroxybutanoyl-CoA:NAD+ oxidoreductase |
R04203 | (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase |
R04737 | (S)-3-hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase |
R04739 | (S)-3-hydroxytetradecanoyl-CoA:NAD+ oxidoreductase |
R04741 | (S)-3-hydroxydodecanoyl-CoA:NAD+ oxidoreductase |
R04743 | (S)-hydroxydecanoyl-CoA:NAD+ oxidoreductase |
R04745 | (S)-hydroxyoctanoyl-CoA:NAD+ oxidoreductase |
R04748 | (S)-hydroxyhexanoyl-CoA:NAD+ oxidoreductase |
R06941 | (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase |
R08094 | 3-hydroxy-5-methylhex-4-enoyl-CoA:NAD+ oxidoreductase |
|
Disease |
H00525 | Disorders of mitochondrial fatty-acid oxidation |
H01267 | Familial hyperinsulinemic hypoglycemia |
H01364 | 3-Hydroxyacyl-CoA dehydrogenase deficiency |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
K00022 HADH; 3-hydroxyacyl-CoA dehydrogenase
09103 Lipid metabolism
00062 Fatty acid elongation
K00022 HADH; 3-hydroxyacyl-CoA dehydrogenase
00071 Fatty acid degradation
K00022 HADH; 3-hydroxyacyl-CoA dehydrogenase
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
K00022 HADH; 3-hydroxyacyl-CoA dehydrogenase
00310 Lysine degradation
K00022 HADH; 3-hydroxyacyl-CoA dehydrogenase
00380 Tryptophan metabolism
K00022 HADH; 3-hydroxyacyl-CoA dehydrogenase
09109 Metabolism of terpenoids and polyketides
00907 Pinene, camphor and geraniol degradation
K00022 HADH; 3-hydroxyacyl-CoA dehydrogenase
09111 Xenobiotics biodegradation and metabolism
00930 Caprolactam degradation
K00022 HADH; 3-hydroxyacyl-CoA dehydrogenase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
K00022 HADH; 3-hydroxyacyl-CoA dehydrogenase
|
Other DBs |
|
Genes |
» show all
|
Reference |
|
Authors |
Vredendaal PJ, van den Berg IE, Malingre HE, Stroobants AK, Olde Weghuis DE, Berger R |
Title |
Human short-chain L-3-hydroxyacyl-CoA dehydrogenase: cloning and characterization of the coding sequence. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Yang SY, He XY, Schulz H |
Title |
3-Hydroxyacyl-CoA dehydrogenase and short chain 3-hydroxyacyl-CoA dehydrogenase in human health and disease. |
Journal |
|
LinkDB |
|