| Entry |
|
|---|
| Name |
Dibutepinephrine hydrochloride (USAN) |
|---|
| Formula |
C17H25NO5. HCl
|
|---|
| Exact mass |
359.1500
|
|---|
| Mol weight |
359.84
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Sympathomimetic |
|---|
| Comment |
Emergency treatment of type 1 allergic reactions, including anaphylaxis
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG03315 Dibutepinephrine
D12935 Dibutepinephrine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D12935 Dibutepinephrine hydrochloride (USAN)
ADRA2
D12935 Dibutepinephrine hydrochloride (USAN)
ADRB
D12935 Dibutepinephrine hydrochloride (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG03315 Dibutepinephrine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 24
1 C8y C 19.8119 -14.2814
2 C8x C 19.8119 -15.6815
3 C8x C 18.6218 -13.5813
4 C1c C 21.0020 -13.5813
5 C8x C 18.6218 -16.3816
6 C8y C 17.3617 -14.2814
7 C1b C 22.1921 -14.2814
8 O1a O 21.0020 -12.1812
9 C8y C 17.3617 -15.6815
10 N1b N 23.4523 -13.5813
11 O7a O 16.1716 -16.3816
12 O7a O 16.1716 -13.5813
13 C1a C 24.6424 -14.2814
14 C7a C 16.1716 -17.7817
15 O6a O 17.3617 -18.4118
16 C1c C 14.9114 -18.4818
17 C1a C 13.7213 -17.7817
18 C1a C 14.9114 -19.8819
19 C7a C 14.9114 -14.2114
20 C1c C 13.7213 -13.5113
21 O6a O 14.9114 -15.6815
22 C1a C 12.5312 -14.2114
23 C1a C 13.7213 -12.1112
24 X Cl 25.2700 -19.8800
BOND 23
1 1 3 1
2 1 4 1
3 2 5 1
4 3 6 2
5 4 7 1
6 4 8 1 #Up
7 5 9 2
8 7 10 1
9 9 11 1
10 6 9 1
11 6 12 1
12 1 2 2
13 10 13 1
14 11 14 1
15 14 15 2
16 14 16 1
17 16 17 1
18 16 18 1
19 12 19 1
20 19 20 1
21 19 21 2
22 20 22 1
23 20 23 1
|
|---|