| Entry |
|
|---|
| Name |
Befunolol hydrochloride (JAN);
Bentos (TN) |
|---|
| Formula |
C16H22NO4. Cl
|
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| Exact mass |
327.1237
|
|---|
| Mol weight |
327.80
|
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| Structure |
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiglaucoma, beta-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01ED Beta blocking agents
S01ED06 Befunolol
D01512 Befunolol hydrochloride (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01138 Befunolol
D01512 Befunolol hydrochloride
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01138 Befunolol
D01512 Befunolol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D01512 Befunolol hydrochloride (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01138 Befunolol
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01138 Befunolol
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 22
1 O2a O 15.4000 -22.6100
2 C1b C 16.6600 -21.9100
3 C1c C 17.8500 -22.6100
4 C1b C 19.0400 -21.9100
5 N1b N 20.3000 -22.6100 #+
6 C1c C 21.4900 -21.9100
7 C1a C 22.6800 -22.6100
8 C1a C 21.4900 -20.5100
9 O1a O 17.8500 -24.0100
10 C8y C 15.4000 -24.0100
11 C8y C 14.1876 -24.7100
12 C8y C 14.1876 -26.1100
13 C8x C 15.4000 -26.8100
14 C8x C 16.6124 -26.1100
15 C8x C 16.6124 -24.7100
16 O2x O 12.8561 -24.2774
17 C8y C 12.0332 -25.4100
18 C8x C 12.8561 -26.5426
19 C5a C 10.6400 -25.4100
20 C1a C 9.9400 -24.1976
21 O5a O 9.9400 -26.6224
22 X Cl 21.0700 -25.1300 #-
BOND 22
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 6 7 1
7 6 8 1
8 3 9 1
9 1 10 1
10 10 11 2
11 11 12 1
12 12 13 2
13 13 14 1
14 14 15 2
15 10 15 1
16 11 16 1
17 16 17 1
18 17 18 2
19 12 18 1
20 17 19 1
21 19 20 1
22 19 21 2
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