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About: Taribavirin

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Taribavirin (rINN; also known as viramidine, codenamed ICN 3142) is an antiviral drug in Phase III human trials, but not yet approved for pharmaceutical use. It is a prodrug of ribavirin, active against a number of DNA and RNA viruses. Taribavirin has better liver-targeting than ribavirin, and has a shorter life in the body due to less penetration and storage in red blood cells. It is expected eventually to be the drug of choice for viral hepatitis syndromes in which ribavirin is active. These include hepatitis C and perhaps also hepatitis B and yellow fever.

Property Value
dbo:abstract
  • Taribavirin (rINN; also known as viramidine, codenamed ICN 3142) is an antiviral drug in Phase III human trials, but not yet approved for pharmaceutical use. It is a prodrug of ribavirin, active against a number of DNA and RNA viruses. Taribavirin has better liver-targeting than ribavirin, and has a shorter life in the body due to less penetration and storage in red blood cells. It is expected eventually to be the drug of choice for viral hepatitis syndromes in which ribavirin is active. These include hepatitis C and perhaps also hepatitis B and yellow fever. (en)
dbo:bioavailability
  • 9.000000 (xsd:float)
dbo:casNumber
  • 119567-79-2
dbo:drugbank
  • none
dbo:fdaUniiCode
  • R3B1994K2E
dbo:kegg
  • D06651
dbo:pubchem
  • 451448
dbo:thumbnail
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  • 3336424 (xsd:integer)
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  • 6200 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1123466481 (xsd:integer)
dbo:wikiPageWikiLink
dbp:alt
  • Ball-and-stick model of the taribavirin molecule (en)
dbp:atcPrefix
  • J05 (en)
dbp:atcSuffix
  • AB04 (en)
dbp:bioavailability
  • 9.0
dbp:c
  • 8 (xsd:integer)
dbp:casNumber
  • 119567 (xsd:integer)
dbp:chemspiderid
  • 397669 (xsd:integer)
dbp:drugbank
  • none (en)
dbp:eliminationHalfLife
  • 424800.0
dbp:excretion
  • 10 (xsd:integer)
dbp:h
  • 13 (xsd:integer)
dbp:image
  • Taribavirin 3D spacefill.png (en)
dbp:iupacName
  • 1 (xsd:integer)
dbp:kegg
  • D06651 (en)
dbp:legalStatus
  • In Phase III drug trials (en)
dbp:metabolism
  • Metabolized to 5'phosphates, de-riboside, and deriboside carboxylic acid (en)
dbp:molecularWeight
  • 243.220000 (xsd:double)
dbp:n
  • 5 (xsd:integer)
dbp:niaidChemdb
  • 198 (xsd:integer)
dbp:o
  • 4 (xsd:integer)
dbp:pregnancyCategory
  • X (en)
dbp:pubchem
  • 451448 (xsd:integer)
dbp:routesOfAdministration
  • Oral capsules) (en)
dbp:smiles
  • n1cCN (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • NHKZSTHOYNWEEZ-AFCXAGJDSA-N (en)
dbp:synonyms
  • 1 (xsd:integer)
  • 124 (xsd:integer)
dbp:unii
  • R3B1994K2E (en)
dbp:verifiedfields
  • changed (en)
dbp:verifiedrevid
  • 470477612 (xsd:integer)
dbp:watchedfields
  • changed (en)
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  • 175 (xsd:integer)
  • 215 (xsd:integer)
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gold:hypernym
rdf:type
rdfs:comment
  • Taribavirin (rINN; also known as viramidine, codenamed ICN 3142) is an antiviral drug in Phase III human trials, but not yet approved for pharmaceutical use. It is a prodrug of ribavirin, active against a number of DNA and RNA viruses. Taribavirin has better liver-targeting than ribavirin, and has a shorter life in the body due to less penetration and storage in red blood cells. It is expected eventually to be the drug of choice for viral hepatitis syndromes in which ribavirin is active. These include hepatitis C and perhaps also hepatitis B and yellow fever. (en)
rdfs:label
  • Taribavirin (en)
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