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About: Rap GTP-binding protein

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Rap GTP-binding protein also known as Ras-related proteins or simply RAP is a type of small GTPase, similar in structure to Ras. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. RAP counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner.

Property Value
dbo:abstract
  • Rap (von Ras-related protein ‚Ras-verwandtes Protein‘) ist eine Proteingruppe kleiner GTPasen aus der . (de)
  • Rap GTP-binding protein also known as Ras-related proteins or simply RAP is a type of small GTPase, similar in structure to Ras. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. RAP counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. (en)
dbo:arm
  • p
  • q
dbo:band
  • 14
  • 13.3
dbo:chromosome
  • 1
  • 12
dbo:entrezgene
  • 5906
  • 5908
dbo:hgncid
  • 9855
  • 9857
dbo:omim
  • 179520 (xsd:integer)
  • 179530 (xsd:integer)
dbo:refseq
  • NM_002884
  • NM_015646
dbo:symbol
  • RAP1A
  • RAP1B
dbo:uniprot
  • P61224
  • P62834
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dbp:arm
  • p (en)
  • q (en)
dbp:band
  • 13.300000 (xsd:double)
  • 14 (xsd:integer)
dbp:chromosome
  • 1 (xsd:integer)
  • 12 (xsd:integer)
dbp:entrezgene
  • 5906 (xsd:integer)
  • 5908 (xsd:integer)
dbp:hgncid
  • 9855 (xsd:integer)
  • 9857 (xsd:integer)
dbp:name
  • dbr:RAP1A
  • RAP1B, (en)
  • member of RAS oncogene family (en)
dbp:omim
  • 179520 (xsd:integer)
  • 179530 (xsd:integer)
dbp:refseq
  • NM_002884 (en)
  • NM_015646 (en)
dbp:symbol
dbp:uniprot
  • P61224 (en)
  • P62834 (en)
dbp:wikiPageUsesTemplate
dct:subject
gold:hypernym
rdf:type
rdfs:comment
  • Rap (von Ras-related protein ‚Ras-verwandtes Protein‘) ist eine Proteingruppe kleiner GTPasen aus der . (de)
  • Rap GTP-binding protein also known as Ras-related proteins or simply RAP is a type of small GTPase, similar in structure to Ras. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. RAP counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. (en)
rdfs:label
  • Rap (Protein) (de)
  • Rap GTP-binding protein (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
foaf:name
  • RAP1B, (en)
  • member of RAS oncogene family (en)
  • RAP1A,member of RAS oncogene family (en)
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