| dbo:abstract
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- The Ras superfamily, derived from "Rat sarcoma virus", is a protein superfamily of small GTPases. Members of the superfamily are divided into families and subfamilies based on their structure, sequence and function. The five main families are Ras, Rho, Ran, Rab and Arf GTPases. The Ras family itself is further divided into 6 subfamilies: Ras, Ral, Rap, Rheb, Rad and Rit. Miro is a recent contributor to the superfamily. Each subfamily shares the common core G domain, which provides essential GTPase and nucleotide exchange activity. The surrounding sequence helps determine the functional specificity of the small GTPase, for example the 'Insert Loop', common to the Rho subfamily, specifically contributes to binding to effector proteins such as WASP. In general, the Ras family is responsible for cell proliferation: Rho for cell morphology, Ran for nuclear transport, and Rab and Arf for vesicle transport. (en)
- Ras超家族（英語：Ras superfamily）是一个蛋白质超家族，名称来自其中的（在人类中为、和）。 Ras超家族中有超过100种蛋白质 ，根据其序列、结构和功能，可分为9个主要的家族，各自还可再分亚家族。这9个蛋白质家族为：、、、、、、、和，Miro最近也被列入这个超家族中。 每个亚家族都有共同的G结构域核心，提供GTP酶与GTP/GDP交换活性。 周围序列有助于确定小GTP酶的功能特异性，例如Rho亚家族常见的“插入环”，特别有助于与效应蛋白如IQGAP和WASP(Wiskott–Aldrich syndrome protein)结合。 通常，Ras家族负责细胞增殖：Rho用于细胞形态，Ran用于核运输，Rab和Arf用于囊泡运输。 (zh)
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| rdfs:comment
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- Ras超家族（英語：Ras superfamily）是一个蛋白质超家族，名称来自其中的（在人类中为、和）。 Ras超家族中有超过100种蛋白质 ，根据其序列、结构和功能，可分为9个主要的家族，各自还可再分亚家族。这9个蛋白质家族为：、、、、、、、和，Miro最近也被列入这个超家族中。 每个亚家族都有共同的G结构域核心，提供GTP酶与GTP/GDP交换活性。 周围序列有助于确定小GTP酶的功能特异性，例如Rho亚家族常见的“插入环”，特别有助于与效应蛋白如IQGAP和WASP(Wiskott–Aldrich syndrome protein)结合。 通常，Ras家族负责细胞增殖：Rho用于细胞形态，Ran用于核运输，Rab和Arf用于囊泡运输。 (zh)
- The Ras superfamily, derived from "Rat sarcoma virus", is a protein superfamily of small GTPases. Members of the superfamily are divided into families and subfamilies based on their structure, sequence and function. The five main families are Ras, Rho, Ran, Rab and Arf GTPases. The Ras family itself is further divided into 6 subfamilies: Ras, Ral, Rap, Rheb, Rad and Rit. Miro is a recent contributor to the superfamily. Each subfamily shares the common core G domain, which provides essential GTPase and nucleotide exchange activity. (en)
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