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About: Jocic reaction

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In organic chemistry, the Jocic reaction, also called the Jocic–Reeve reaction (named after Zivojin Jocic and Wilkins Reeve) is a name reaction that generates α-substituted carboxylic acids from trichloromethylcarbinols and corresponding nucleophiles in the presence of sodium hydroxide. The reaction involves nucleophilic displacement of the hydroxyl group in a 1,1,1-trichloro-2-hydroxyalkyl structure with concomitant conversion of the trichloromethyl portion to a carboxylic acid or similar functional group.

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  • In organic chemistry, the Jocic reaction, also called the Jocic–Reeve reaction (named after Zivojin Jocic and Wilkins Reeve) is a name reaction that generates α-substituted carboxylic acids from trichloromethylcarbinols and corresponding nucleophiles in the presence of sodium hydroxide. The reaction involves nucleophilic displacement of the hydroxyl group in a 1,1,1-trichloro-2-hydroxyalkyl structure with concomitant conversion of the trichloromethyl portion to a carboxylic acid or similar functional group. (en)
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  • Jocic reaction (en)
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  • Wilkins Reeve (en)
  • Zivojin Jocic (en)
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  • Substitution reaction (en)
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  • In organic chemistry, the Jocic reaction, also called the Jocic–Reeve reaction (named after Zivojin Jocic and Wilkins Reeve) is a name reaction that generates α-substituted carboxylic acids from trichloromethylcarbinols and corresponding nucleophiles in the presence of sodium hydroxide. The reaction involves nucleophilic displacement of the hydroxyl group in a 1,1,1-trichloro-2-hydroxyalkyl structure with concomitant conversion of the trichloromethyl portion to a carboxylic acid or similar functional group. (en)
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  • Jocic reaction (en)
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