Charles LoPresti (born September 21, 1957) is an American race horse trainer best known as trainer of two-time Breeders' Cup Mile winner and Eclipse Award for Horse of the Year champion Wise Dan, who was also American Champion Older Male Horse and American Champion Male Turf Horse. Unusual for modern American horse trainers, he is based year-round at Keeneland Race Course and does not move his training stable from track to track throughout the year. He chooses to give his horses time off in the winter and does not race-year-round.