We investigate the physics potential of the upcoming Deep Underground Neutrino Experiment (DUNE) in probing active-sterile mixing. We present analytic expressions for relevant oscillation probabilities for three active and one sterile neutrino of eV-scale mass and highlight essential parameters impacting the oscillation signals at DUNE. We then explore the space of sterile parameters as well as study their correlations among themselves and with parameters appearing in the standard framework ( and ). We perform a combined fit for the near and far detector at DUNE using GLoBES. We consider alternative beam tune (low energy and medium energy) and runtime combinations for constraining the sterile parameter space. We show that charged current and neutral current interactions over the near and far detector at DUNE allow for an improved sensitivity for a wide range of sterile neutrino mass splittings.