Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40

…, H Kizawa, H Komatsu, F Matsumura, Y Noguchi… - Nature, 2003 - nature.com
Diabetes, a disease in which carbohydrate and lipid metabolism are regulated improperly by
insulin, is a serious worldwide health issue 1 , 2 . Insulin is secreted from pancreatic β cells …

Adipose‐derived mesenchymal stem cells and regenerative medicine

…, K Ohta, Y Kano, M Ozaki, Y Noguchi… - Development …, 2013 - Wiley Online Library
Adipose tissue‐derived mesenchymal stem cells ( ADSC s) are multipotent and can
differentiate into various cell types, including osteocytes, adipocytes, neural cells, vascular …

Identification of a G protein-coupled receptor specifically responsive to β-alanine

…, S Fukusumi, H Komatsu, M Hosoya, Y Noguchi… - Journal of Biological …, 2004 - ASBMB
We isolated a cDNA encoding an orphan G protein-coupled receptor, TGR7, which has been
recently reported to correspond to MrgD. To search for ligands for TGR7, we screened a …

Depletion of JARID1B induces cellular senescence in human colorectal cancer

…, T Mizushima, Y Noguchi… - International …, 2013 - spandidos-publications.com
The global incidence of colorectal cancer (CRC) is increasing. Although there are emerging
epigenetic factors that contribute to the occurrence, development and metastasis of CRC, …

Association between thyroid cysts and hypertension by atherosclerosis status: A cross-sectional study

Y Shimizu, SY Kawashiri, Y Noguchi, Y Nagata… - Scientific Reports, 2021 - nature.com
Our recent studies indicate that thyroid cysts have clinical implications. Thyroid cysts could
have a positive effect on the supply of thyroid hormones. Both hyperthyroidism and …

InSAR-derived crustal deformation and fault models of normal faulting earthquake (Mj 7.0) in the Fukushima-Hamadori area

…, M Koarai, T Okatani, A Suzuki, Y Noguchi… - Earth, planets and …, 2012 - Springer
Applying interferometric SAR (InSAR) analysis using ALOS/PALSAR data to inland crustal
earthquakes in the Fukushima-Hamadori area, we succeeded in mapping a ground …

Vascular endothelial growth factor (VEGF) polymorphism rs3025039 and atherosclerosis among older with hypertension

Y Shimizu, K Arima, Y Noguchi, H Yamanashi… - Scientific Reports, 2022 - nature.com
Angiogenesis inhibition therapy causes hypertension by increasing peripheral vascular
resistance. Vasa vasorum angiogenesis plays a crucial role in the development of …

Crustal deformation map for the 2011 off the Pacific coast of Tohoku Earthquake, detected by InSAR analysis combined with GEONET data

…, M Tobita, T Nishimura, A Suzuki, Y Noguchi… - Earth, planets and …, 2011 - Springer
Applying interferometric SAR (InSAR) analysis using ALOS/PALSAR data to a megathrust
earthquake (M w 9.0) that ruptured off-shore of Tohoku, Japan, on 11 March, 2011, we …

Eldecalcitol for the treatment of osteoporosis

Y Noguchi, H Kawate, M Nomura… - Clinical interventions in …, 2013 - Taylor & Francis
Eldecalcitol (1α, 25-dihydroxy-2β-[3-hydroxypropyloxy] vitamin D 3 ; ED-71) is a new analog
of the active form of vitamin D. Eldecalcitol has recently been approved for the treatment of …

Jumonji/Arid1b (Jarid1b) protein modulates human esophageal cancer cell growth

…, H Ogawa, T Fukusumi, Y Noguchi… - Molecular and …, 2013 - spandidos-publications.com
Although esophageal cancer is highly heterogeneous and the involvement of epigenetic
regulation of cancer stem cells is highly suspected, the biological significance of epigenetically …