Deep brain stimulation (DBS) is a safe and innovative neuromodulatory therapy applied in
multiple neurologic disorders including movement disorders, dementia, epilepsy, …

Seizure semiology represents the clinical expression of the activation of the several brain
regions comprising an epileptic network. In mesial temporal lobe epilepsy (MTLE), this network …

Background Pregabalin (PGB) is an effective adjunctive treatment for focal epilepsy and
acts by binding to the alpha2-delta subunit of voltage-gated calcium channels to reduce …

Intracranial electroencephalography (iEEG) presents a unique opportunity to extend human
neuroscientific understanding. However, typically iEEG is collected from patients diagnosed …

Objective: To report a case of a patient with intractable epilepsy from adult onset Rasmussen’s
encephalitis (RE) who responded to tocilizumab therapy. Background: Adult onset RE …

Objective: To share our multi-center experience with Pregabalin (PGB) in neurocritically ill
patients with refractory seizures. Background: PGB is an approved adjunctive treatment for …

Objective: Compare the cost-benefits of ambulatory and inpatient 24 hour EEG studies.
Background: Prolonged EEG recordings have a higher yield of diagnostic findings compared to …

Introduction Although admission into an epilepsy monitoring unit (EMU) has been the
standard modality in the evaluation of epilepsy and paroxysmal spells, ambulatory …

Background: Bipolar disorder (BD) is a disabling disorder whereby individuals suffer from
episodes of mania and depression. The mode of inheritance of BD is complex and likely …

… DEDICATION Dedicated to my husband Sotiris Mitropanopoulos for his unwavering
support, sacrifice and love, and to the rest of my family: Ben Barnhart, Daniel Barnhart, Richard …