Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migration

…, CM Hale, P Panorchan, SB Khatau, JP George… - Biophysical journal, 2007 - cell.com
Lamin A/C is a major constituent of the nuclear lamina, a thin filamentous protein layer that
lies beneath the nuclear envelope. Here we show that lamin A/C deficiency in mouse …

Fibronectin fibrillogenesis regulates three-dimensional neovessel formation

X Zhou, RG Rowe, N Hiraoka, JP George… - Genes & …, 2008 - genesdev.cshlp.org
During vasculogenesis and angiogenesis, endothelial cell responses to growth factors are
modulated by the compositional and mechanical properties of a surrounding three-…

Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking

RJ Bloom, JP George, A Celedon, SX Sun, D Wirtz - Biophysical journal, 2008 - cell.com
Mesenchymal cell migration through a three-dimensional (3D) matrix typically involves major
matrix remodeling. The direction of matrix deformation occurs locally in all three dimensions…

Variations in the RBE for cell killing along the depth-dose profile of a modulated proton therapy beam

…, M Wolanski, X Nie, J George… - Radiation …, 2013 - meridian.allenpress.com
Considerable evidence now exists to show that that the relative biological effectiveness (RBE)
changes considerably along the proton depth-dose distribution, with progressively higher …

Probing intercellular interactions between vascular endothelial cadherin pairs at single-molecule resolution and in living cells

P Panorchan, JP George, D Wirtz - Journal of molecular biology, 2006 - Elsevier
Vascular endothelial (VE) cadherin is the surface glycoprotein cadherin specific to the
endothelium that mediates cell–cell adhesion and plays a major role in the remodeling, gating, …

Association of delay in appendectomy with perforation in children with appendicitis

…, S Kunkov, JH Chao, ET Tay, JP George… - Pediatric Emergency …, 2019 - journals.lww.com
Objective The aim of this study was to assess whether increased time from emergency
department (ED) triage to appendectomy is associated with a greater risk of children developing …

Microbiological profile of septic arthritis in adults: Lessons learnt and treatment strategies

J George, VJ Chandy, J Premnath, TD Hariharan… - Indian journal of medical …, 2019 - Elsevier
Objective: The aim of this study is to characterise the clinical and microbiological profile of
adult patients treated at our orthopaedic unit with septic arthritic between 2006 and 2017. …

Comparison between quadriceps muscle strengthening on land and in water

M Petrick, T Paulsen, J George - Physiotherapy, 2001 - Elsevier
A study on healthy young women compared progressive resistance quadriceps muscle
strengthening in water and on land. The water (n = 19) and the land (n = 18) groups exercised …

[HTML][HTML] Effectiveness of Yoga in Modulating Markers of Immunity and Inflammation: A Systematic Review and Meta-Analysis

B Mishra, A Agarwal, JA George, AD Upadhyay… - Cureus, 2024 - ncbi.nlm.nih.gov
Chronic inflammation is central to the pathogenesis of many chronic inflammatory conditions.
This review aims to analyze whether the practice of yoga, or yogic meditation and breathing…

Incidence of mortality in 1,040 patients with coronary heart disease or hypertensive heart disease with normal and abnormal left ventricular ejection fraction and with …

…, A Rachdev, A Asija, KV Lai, J George… - Archives of Medical …, 2008 - termedia.pl
Results: Mean follow-up was 17±10 months. Death occurred in 65 (11%) of 598 patients
with a normal QRS duration and a normal LVEF [1], in 19 (19%) of 100 patients with an …